Brown Rebecca J, Nguipdop-Djomo Patrick, Zhao Hongxin, Stanford Elaine, Spiller O Brad, Chalker Victoria J
Public Health EnglandLondon, UK; Department of Child Health, University Hospital Wales, Cardiff University School of MedicineCardiff, UK.
Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine London, UK.
Front Microbiol. 2016 Feb 16;7:157. doi: 10.3389/fmicb.2016.00157. eCollection 2016.
Investigations of patients with suspected Mycoplasma pneumoniae infection have been undertaken in England since the early 1970s. M. pneumoniae is a respiratory pathogen that is a common cause of pneumonia and may cause serious sequelae such as encephalitis and has been documented in children with persistent cough. The pathogen is found in all age groups, with higher prevalence in children aged 5-14 years. In England, recurrent epidemic periods have occurred at ~4-yearly intervals. In addition, low-level sporadic infection occurs with seasonal peaks from December to February. Voluntarily reports from regional laboratories and hospitals in England from 1975 to 2015 were collated by Public Health England for epidemiological analysis. Further data pertaining cases of note and specimens submitted to Public Health England from 2005 to 2015 for confirmation, molecular typing is included.
自20世纪70年代初以来，英国一直在对疑似肺炎支原体感染的患者进行调查。肺炎支原体是一种呼吸道病原体，是肺炎的常见病因，可能导致严重的后遗症，如脑炎，在持续咳嗽的儿童中也有记录。该病原体在所有年龄组中都有发现，在5至14岁的儿童中患病率更高。在英国，疫情每隔约4年就会复发一次。此外，还会出现低水平的散发性感染，在12月至2月有季节性高峰。英国公共卫生部门整理了1975年至2015年英格兰地区实验室和医院的自愿报告，用于流行病学分析。还纳入了2005年至2015年提交给英国公共卫生部门进行确认、分子分型的值得注意的病例和标本的进一步数据。
