Krishnan Pradeep, Shroff Manohar
Department of Pediatric Neuroimaging, Hospital for Sick Children, Toronto, Ontario, Canada.
Indian J Pediatr. 2016 Sep;83(9):995-1002. doi: 10.1007/s12098-016-2042-1. Epub 2016 Feb 24.
Magnetic resonance (MR) imaging is emerging as one of the most important tools in identifying the etiology of neonatal encephalopathy as well as in predicting long-term outcomes. This makes it imperative to have a broader understanding of normal myelination of the neonatal brain on MR imaging and to be familiar with the spectrum of imaging features in ischemic and non-ischemic neonatal encephalopathy. Hypoxic ischemic injury (HIE) is one of the most common causes of neonatal encephalopathy and imaging appearances are influenced by factors such as the stage of maturation of the neonatal brain and severity as well as duration of ischemic insult. Other common causes of neonatal encephalopathy include infectious diseases, congenital disorders and inborn errors of metabolism.
磁共振成像（MR）正成为识别新生儿脑病病因以及预测长期预后的最重要工具之一。因此，有必要更广泛地了解新生儿脑在MR成像上的正常髓鞘形成，并熟悉缺血性和非缺血性新生儿脑病的成像特征谱。缺氧缺血性损伤（HIE）是新生儿脑病最常见的病因之一，其影像表现受新生儿脑成熟阶段、缺血损伤的严重程度和持续时间等因素影响。新生儿脑病的其他常见病因包括传染病、先天性疾病和先天性代谢缺陷。
