Rahiminejad Mohammad, Haghighi Abdalrahman, Dastan Alireza, Abouali Omid, Farid Mehrdad, Ahmadi Goodarz
School of Mechanical Engineering, Shiraz University, Shiraz, Iran; School of Mechanical Engineering, Sharif University of Technology, Azadi Avenue, Tehran, Iran.
School of Mechanical Engineering, Shiraz University, Shiraz, Iran.
Comput Biol Med. 2016 Apr 1;71:115-27. doi: 10.1016/j.compbiomed.2016.01.022. Epub 2016 Feb 2.
In this paper, the airflow field including the velocity, pressure and turbulence intensity distributions during sneezing of a female subject was simulated using a computational fluid dynamics model of realistic upper airways including both oral and nasal cavities. The effects of variation of reaction of the subject during sneezing were also investigated. That is, the impacts of holding the nose or closing the mouth during sneezing on the pressure and velocity distributions were studied. Few works have studied the sneeze and therefore different aspects of this phenomenon have remained unknown. To cover more possibilities about the inlet condition of trachea in different sneeze scenarios, it was assumed that the suppressed sneeze happens with either the same inlet pressure or the same flow rate as the normal sneeze. The simulation results showed that during a normal sneeze, the pressure in the trachea reaches about 7000Pa, which is much higher than the pressure level of about 200Pa during the high activity exhalation. In addition, the results showed that, suppressing the sneeze by holding the nose or mouth leads to a noticeable increase in pressure difference in the tract. This increase was about 5 to 24 times of that during a normal sneeze. This significant rise in the pressure can justify some reported damage due to suppressing a sneeze.
在本文中,使用包含口腔和鼻腔的真实上呼吸道计算流体动力学模型,模拟了一名女性受试者打喷嚏时的气流场,包括速度、压力和湍流强度分布。还研究了受试者在打喷嚏过程中反应变化的影响。也就是说,研究了打喷嚏时捏鼻或闭嘴对压力和速度分布的影响。很少有研究涉及打喷嚏,因此这一现象的不同方面仍不为人知。为了涵盖不同打喷嚏场景下气管入口条件的更多可能性,假设抑制性喷嚏与正常喷嚏具有相同的入口压力或相同的流速。模拟结果表明,在正常打喷嚏过程中,气管内的压力达到约7000Pa,远高于高活动度呼气时约200Pa的压力水平。此外,结果表明,通过捏鼻或闭嘴抑制喷嚏会导致呼吸道内压力差显著增加。这种增加约为正常打喷嚏时的5至24倍。压力的显著升高可以解释一些因抑制喷嚏而报告的损伤。