Stranieri Angelica, Ferrari Roberta, Zanzani Sergio, Rossi Gabriele
Department of Veterinary Science and Public Health, University of Milan, Milan, Italy.
School of Veterinary and Life Science, Murdoch University, Murdoch, WA, Australia.
Vet Clin Pathol. 2016 Jun;45(2):225-228. doi: 10.1111/vcp.12340. Epub 2016 Feb 26.
A 13-year-old female Domestic Shorthair cat was presented to the Veterinary Teaching Hospital of the University of Milan for an interscapular mass suspected to be a mesenchymal malignant tumor. A preoperative CBC performed with Sysmex XT-2000iV showed leukocytosis with neutrophilia and eosinophilia. The Sysmex WBC/DIFF scattergram showed an additional, well-separated cluster of events between the neutrophil, eosinophil, and lymphocyte clusters. Blood smear evaluation revealed the presence of a significant number of basophils; thus, it was hypothesized that the additional cluster could represent the basophilic population. A second CBC, 24 days later, showed the same pattern on the WBC/DIFF scattergram in the absence of leukocytosis and neutrophilia. After surgical excision of the mass, a definitive diagnosis of feline injection site sarcoma was made. To the author's knowledge, there are no previous reports about the identification of feline basophils in the WBC/DIFF scattergram of Sysmex XT-2000iV.
一只13岁的雌性家养短毛猫被送至米兰大学兽医教学医院，其肩胛间有一肿块，怀疑是间叶性恶性肿瘤。使用Sysmex XT - 2000iV进行的术前全血细胞计数显示白细胞增多，伴有中性粒细胞增多和嗜酸性粒细胞增多。Sysmex白细胞分类散点图显示在中性粒细胞、嗜酸性粒细胞和淋巴细胞群之间有另外一群分离良好的事件。血涂片评估显示存在大量嗜碱性粒细胞；因此，推测另外一群细胞可能代表嗜碱性粒细胞群。24天后的第二次全血细胞计数显示，在没有白细胞增多和中性粒细胞增多的情况下，白细胞分类散点图呈现相同模式。肿块手术切除后，最终诊断为猫注射部位肉瘤。据作者所知，之前尚无关于在Sysmex XT - 2000iV的白细胞分类散点图中识别猫嗜碱性粒细胞的报道。
