Xie Xiaojiang
Department of Inorganic and Analytical Chemistry, University of Geneva, Quai Ernest Ansermet 30, 1211, Geneva 4, Switzerland.
Anal Bioanal Chem. 2016 Apr;408(11):2717-25. doi: 10.1007/s00216-016-9406-2. Epub 2016 Feb 27.
Ion-selective optical sensing is an important branch of analytical and bioanalytical chemistry. Conventional ion-selective optodes are based on H(+) chromoionophores. These sensors are known to be pH dependent and usually operated in a passive mode. In view of the applications in complex real samples, the sensors must exhibit not only excellent chemical selectivity but also the ability to eliminate the optical background interference such as autofluorescence and light scattering. In this article, recent advances to renovate the chromoionophores and detection modes to overcome the pH cross-response and to eliminate the background optical interference are summarized. Topics include sensors based on solvatochromic dyes, alternative chromoionophores, photoswitchable sensors, upconverting nanoparticles, luminescence decay time, and others.
离子选择性光学传感是分析化学和生物分析化学的一个重要分支。传统的离子选择性光极基于H(+)发色离子载体。已知这些传感器依赖于pH值，并且通常以被动模式运行。鉴于在复杂实际样品中的应用，传感器不仅必须表现出优异的化学选择性，还必须具备消除诸如自发荧光和光散射等光学背景干扰的能力。本文总结了为克服pH交叉响应和消除背景光学干扰而对发色离子载体和检测模式进行革新的最新进展。主题包括基于溶剂化显色染料的传感器、替代发色离子载体、光开关传感器、上转换纳米颗粒、发光衰减时间等。
