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The Microbiome in Critical Illness: Firm Conclusions or Bact to Square One?

作者信息

Lyons John D, Ford Mandy L, Coopersmith Craig M

机构信息

Emory Critical Care Center and Department of Surgery, Emory Healthcare and Emory University School of Medicine, 101 Woodruff Circle, Suite WMB 5105, Atlanta, GA, 30322, USA.

Emory Transplant Center and Department of Surgery, Emory Healthcare and Emory University School of Medicine, 101 Woodruff Circle, Suite WMB 5105, Atlanta, GA, 30322, USA.

出版信息

Dig Dis Sci. 2016 Jun;61(6):1420-1. doi: 10.1007/s10620-016-4092-7.

DOI:10.1007/s10620-016-4092-7
PMID:26923947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4875832/
Abstract
摘要

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Dig Dis Sci. 2016 Jun;61(6):1628-34. doi: 10.1007/s10620-015-4011-3. Epub 2015 Dec 29.
2
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota.通过CTLA-4阻断进行的抗癌免疫疗法依赖于肠道微生物群。
Science. 2015 Nov 27;350(6264):1079-84. doi: 10.1126/science.aad1329. Epub 2015 Nov 5.
3
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy.共生双歧杆菌可促进抗肿瘤免疫并增强抗程序性死亡受体配体1（PD-L1）的疗效。
Science. 2015 Nov 27;350(6264):1084-9. doi: 10.1126/science.aac4255. Epub 2015 Nov 5.
4
Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site.自身反应性T细胞受体的微生物群依赖性激活在免疫赦免部位引发自身免疫。
Immunity. 2015 Aug 18;43(2):343-53. doi: 10.1016/j.immuni.2015.07.014.
5
Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak.粪肠球菌引起的胶原蛋白降解和MMP9激活会导致肠道吻合口漏。
Sci Transl Med. 2015 May 6;7(286):286ra68. doi: 10.1126/scitranslmed.3010658.
6
The opposing forces of the intestinal microbiome and the emerging pathobiome.肠道微生物群与新兴病理生物群的对抗力量。
Surg Clin North Am. 2014 Dec;94(6):1151-61. doi: 10.1016/j.suc.2014.08.002. Epub 2014 Oct 7.
7
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