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[维生素D和钙在肥胖症及2型糖尿病中的作用]

[Role of vitamin D and calcium in obesity and type 2 diabetes].

作者信息

Kuroda Masashi, Sakaue Hiroshi

机构信息

Department of Nutrition and Metabolism, Institute of Biomedical Sciences,Tokushima University Graduate School, Japan.

出版信息

Clin Calcium. 2016 Mar;26(3):349-54.

PMID:26923970
Abstract

Obesity, induced by unhealthy lifestyle choices, could be involved in the development of chronic diseases like type 2 diabete. Obesity is largely due to the imbalance of energy intake and expenditure, therefore we have put more emphasis on the amount of macronutrients including carbohydrates, fats and proteins as dietary therapy for obesity and related-conditions. On the other hand, several studies revealed obese or diabetic patients were more likely to have micronutrient deficiencies such as vitamins and minerals. Besides the effects on bone metabolism, vitamin D and calcium might contribute to metabolic disorder accompanied by obesity. However, it has not been concluded supplementation of these two nutrients has a benefit in obese or diabetic individuals. Further studies are needed.

摘要

由不健康的生活方式选择导致的肥胖,可能与2型糖尿病等慢性疾病的发生有关。肥胖主要是由于能量摄入与消耗的失衡,因此我们更加注重包括碳水化合物、脂肪和蛋白质在内的常量营养素的摄入量,将其作为肥胖及相关病症的饮食疗法。另一方面,多项研究表明,肥胖或糖尿病患者更有可能缺乏维生素和矿物质等微量营养素。除了对骨骼代谢的影响外,维生素D和钙可能会导致伴随肥胖的代谢紊乱。然而,尚未得出补充这两种营养素对肥胖或糖尿病个体有益的结论。还需要进一步的研究。

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[Role of vitamin D and calcium in obesity and type 2 diabetes].[维生素D和钙在肥胖症及2型糖尿病中的作用]
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1,25-二羟维生素 D3 治疗可减轻 Goto-Kakizaki 型 2 型糖尿病模型大鼠的骨质疏松症,并改善其骨肌质量。
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[Effect of vitamin D deficiency on cardiac autonomic nerve function in obese pre-school children].维生素D缺乏对肥胖学龄前儿童心脏自主神经功能的影响
Zhongguo Dang Dai Er Ke Za Zhi. 2018 Sep;20(9):753-757. doi: 10.7499/j.issn.1008-8830.2018.09.012.
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Dietary Protein Consumption and the Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis of Cohort Studies.饮食蛋白质摄入与 2 型糖尿病风险:队列研究的系统评价和荟萃分析。
Nutrients. 2017 Sep 6;9(9):982. doi: 10.3390/nu9090982.
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