Melamed Philippa, Yosefzon Yahav, Rudnizky Sergei, Pnueli Lilach
a Faculty of Biology, Technion-Israel Institute of Technology , Haifa , Israel.
Transcription. 2016;7(1):26-31. doi: 10.1080/21541264.2015.1128517.
Active transcriptional enhancers are often transcribed to eRNAs, whose changing levels mirror those of the target gene mRNA. We discuss some of the reported functions of these eRNAs and their likely diversity to allow utilization of distinct cis regulatory regions to enhance transcription in diverse developmental and cellular contexts.
活跃的转录增强子通常转录为eRNA，其水平变化反映了靶基因mRNA的水平变化。我们讨论了这些eRNA的一些已报道功能及其可能的多样性，以便利用不同的顺式调控区域在不同的发育和细胞环境中增强转录。
