基于正念和接纳的精神病干预措施：系统评价与荟萃分析。
Mindfulness- and Acceptance-based Interventions for Psychosis: A Systematic Review and Meta-analysis.
作者信息
Cramer Holger, Lauche Romy, Haller Heidemarie, Langhorst Jost, Dobos Gustav
机构信息
Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney (Dr Cramer), Australia.
Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney (Dr Lauche), Australia.
出版信息
Glob Adv Health Med. 2016 Jan;5(1):30-43. doi: 10.7453/gahmj.2015.083. Epub 2016 Jan 1.
BACKGROUND
Mindfulness- and acceptance-based interventions are increasingly studied as a potential treatment for a variety of mental conditions.
OBJECTIVE
To assess the effects of mindfulness- and acceptance-based interventions on psychotic symptoms and hospitalization in patients with psychosis.
METHODS
MEDLINE/PubMed, Embase, the Cochrane Library, and PsycINFO were screened from inception through April 2015. Randomized controlled trials (RCTs) were analyzed when they assessed psychotic symptoms or hospitalization in patients with psychosis; affect, acceptance, mindfulness, and safety were defined as secondary outcomes.
RESULTS
Eight RCTs with a total of 434 patients comparing mindfulness-based (4 RCTs) or acceptance-based interventions (4 RCTs) to treatment as usual or attention control were included. Six RCTs had low risk of bias. Moderate evidence was found for short-term effects on total psychotic symptoms, positive symptoms, hospitalization rates, duration of hospitalization, and mindfulness and for long-term effects on total psychotic symptoms and duration of hospitalization. No evidence was found for effects on negative symptoms, affect, or acceptance. No serious adverse events were reported.
CONCLUSION
Mindfulness- and acceptance-based interventions can be recommended as an additional treatment for patients with psychosis.
背景
基于正念和接纳的干预措施作为多种精神疾病的潜在治疗方法正受到越来越多的研究。
目的
评估基于正念和接纳的干预措施对精神病患者的精神病性症状及住院情况的影响。
方法
检索了从数据库建立至2015年4月的MEDLINE/PubMed、Embase、Cochrane图书馆和PsycINFO。纳入评估精神病患者精神病性症状或住院情况的随机对照试验（RCT）；将情感、接纳、正念和安全性定义为次要结局。
结果
纳入了八项RCT，共434例患者，比较了基于正念的干预措施（4项RCT）或基于接纳的干预措施（4项RCT）与常规治疗或注意力控制。六项RCT存在低偏倚风险。发现有中等证据表明其对总精神病性症状、阳性症状、住院率、住院时长、正念有短期影响，对总精神病性症状和住院时长有长期影响。未发现对阴性症状、情感或接纳有影响的证据。未报告严重不良事件。
结论
基于正念和接纳的干预措施可推荐作为精神病患者的一种辅助治疗方法。
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