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连接肠道微生物群与葡萄糖代谢的机制

Mechanisms Linking the Gut Microbiome and Glucose Metabolism.

作者信息

Utzschneider Kristina M, Kratz Mario, Damman Chris J, Hullar Meredith

机构信息

Division of Metabolism, Endocrinology and Nutrition (K.M.U.), Department of Medicine, VA Puget Sound Health Care System and the University of Washington, Seattle, Washington; Division of Public Health Sciences (M.K.), Fred Hutchinson Cancer Research Center, and the Department of Epidemiology, University of Washington, Seattle, Washington; Division of Gastroenterology (C.J.D.), Department of Medicine, University of Washington, Seattle, Washington; and Division of Public Health Sciences (M.H.), Fred Hutchinson Cancer Research Center, Seattle, Washington.

出版信息

J Clin Endocrinol Metab. 2016 Apr;101(4):1445-54. doi: 10.1210/jc.2015-4251. Epub 2016 Mar 3.

Abstract

This review details potential mechanisms linking gut dysbiosis to metabolic dysfunction, including lipopolysaccharide, bile acids, short chain fatty acids, gut hormones, and branched-chain amino acids.

摘要

本综述详细阐述了将肠道菌群失调与代谢功能障碍联系起来的潜在机制,包括脂多糖、胆汁酸、短链脂肪酸、肠道激素和支链氨基酸。

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