Basak Silpi, Singh Priyanka, Rajurkar Monali
Department of Microbiology, Jawaharlal Nehru Medical College, Wardha 442004, India.
J Pathog. 2016;2016:4065603. doi: 10.1155/2016/4065603. Epub 2016 Jan 28.
Background and Objective. Antimicrobial resistance is now a major challenge to clinicians for treating patients. Hence, this short term study was undertaken to detect the incidence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates in a tertiary care hospital. Material and Methods. The clinical samples were cultured and bacterial strains were identified in the department of microbiology. The antibiotic susceptibility profile of different bacterial isolates was studied to detect MDR, XDR, and PDR bacteria. Results. The antibiotic susceptibility profile of 1060 bacterial strains was studied. 393 (37.1%) bacterial strains were MDR, 146 (13.8%) strains were XDR, and no PDR was isolated. All (100%) Gram negative bacterial strains were sensitive to colistin whereas all (100%) Gram positive bacterial strains were sensitive to vancomycin. Conclusion. Close monitoring of MDR, XDR, or even PDR must be done by all clinical microbiology laboratories to implement effective measures to reduce the menace of antimicrobial resistance.
背景与目的。抗菌药物耐药性现已成为临床医生治疗患者面临的一项重大挑战。因此,开展了这项短期研究,以检测一家三级护理医院中多重耐药(MDR)、广泛耐药(XDR)和泛耐药(PDR)细菌分离株的发生率。材料与方法。临床样本在微生物学部门进行培养并鉴定细菌菌株。研究不同细菌分离株的抗生素敏感性谱,以检测MDR、XDR和PDR细菌。结果。研究了1060株细菌菌株的抗生素敏感性谱。393株(37.1%)细菌菌株为MDR,146株(13.8%)菌株为XDR,未分离到PDR菌株。所有(100%)革兰氏阴性细菌菌株对黏菌素敏感,而所有(100%)革兰氏阳性细菌菌株对万古霉素敏感。结论。所有临床微生物实验室必须密切监测MDR、XDR甚至PDR情况,以实施有效措施减少抗菌药物耐药性的威胁。