Sobouti Behnam, Mirshekar Maryam, Fallah Shahrzad, Tabaei Aram, Fallah Mehrabadi Jalil, Darbandi Atieh
Burn Research Center, Iran University of Medical Sciences, Tehran, Iran.
Student Research Committee, Iran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2020 Mar 23;34:24. doi: 10.34171/mjiri.34.24. eCollection 2020.
Nosocomial infection caused by has emerged as a world-wide serious problem in the emergence of multidrug-resistant (MDR). Infections caused by antibiotic-resistant strains of cannot be completely eliminated among the infected patients. This study aimed to monitor antibiotic resistance among strains isolated from burnt children. After performing biochemical identification tests on 115 isolates, 62 were detected as . Minimum inhibitory concentration (MIC) was used to test susceptibility to colistin, and disk agar diffusion was used for the susceptibility of the isolates to the antibiotics Ciprofloxacin, Amikacin, Gentamicin, Cefepime, Meropenem, Imipenem, Ceftazidime, Levofloxacin and Piperacillin/Tazobactam. Bacterial species were isolated and identified as multidrug-resistant (MDR), extensively drug-resistant (XDR) and pan drug-resistant (PDR), based on the susceptibility patterns to elected antibiotics, deputing different classes of antimicrobial. The antibiotic susceptibility pattern out of a total of 62 bacterial strains used in this study. Thirty-six (58%) strains were categorized as MDR, 17 (27.5%) as XDR, and nine (14.5%) as PDR. To reduce the threat of antimicrobial resistance, MDR, XDR and PDR strains must be evaluated by all clinical microbiology laboratories.
在多重耐药(MDR)出现的情况下,由[细菌名称未给出]引起的医院感染已成为一个全球性的严重问题。在感染患者中,由抗生素耐药菌株引起的感染无法完全消除。本研究旨在监测从烧伤儿童中分离出的[细菌名称未给出]菌株的抗生素耐药性。对115株分离株进行生化鉴定试验后,检测到62株为[细菌名称未给出]。采用最低抑菌浓度(MIC)检测对黏菌素的敏感性,采用纸片琼脂扩散法检测分离株对环丙沙星、阿米卡星、庆大霉素、头孢吡肟、美罗培南、亚胺培南、头孢他啶、左氧氟沙星和哌拉西林/他唑巴坦等抗生素的敏感性。根据对选定抗生素(代表不同类别的抗菌药物)的敏感性模式,将分离出的细菌种类鉴定为多重耐药(MDR)、广泛耐药(XDR)和泛耐药(PDR)。本研究共使用了62株细菌菌株的抗生素敏感性模式。三十六株(58%)菌株被归类为MDR,十七株(27.5%)为XDR,九株(14.5%)为PDR。为降低抗菌药物耐药性的威胁,所有临床微生物实验室都必须对MDR、XDR和PDR[细菌名称未给出]菌株进行评估。