• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用奥克托克斯组合纸片法检测克雷伯菌属中的超广谱β-内酰胺酶

Detection of extended-spectrum beta-lactamases in klebsiellae with the Oxoid combination disk method.

作者信息

Carter M W, Oakton K J, Warner M, Livermore D M

机构信息

Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT, United Kingdom.

出版信息

J Clin Microbiol. 2000 Nov;38(11):4228-32. doi: 10.1128/JCM.38.11.4228-4232.2000.

DOI:10.1128/JCM.38.11.4228-4232.2000
PMID:11060096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC87569/
Abstract

The Oxoid combination disk method for detecting extended-spectrum beta-lactamases (ESBLs) depends on comparing the inhibition zones of cefpodoxime (10-microg) and cefpodoxime-plus-clavulanate (10- plus 1-microg) disks. The presence of clavulanate enlarged the zones for all of 180 ESBL-producing klebsiellae by >/=5 mm, whereas zones for cefpodoxime-susceptible isolates and cefpodoxime-resistant isolates with AmpC and K1 beta-lactamases were enlarged by </=1 mm. Good discrimination was achieved with either the NCCLS or the British disk method.

摘要

用于检测超广谱β-内酰胺酶（ESBLs）的奥克托克斯组合纸片法，是通过比较头孢泊肟（10微克）和头孢泊肟加克拉维酸（10微克加1微克）纸片的抑菌圈来进行的。克拉维酸的存在使180株产ESBLs的克雷伯菌的抑菌圈均扩大了≥5毫米，而对头孢泊肟敏感的菌株以及产AmpC和K1β-内酰胺酶的头孢泊肟耐药菌株的抑菌圈扩大≤1毫米。无论是采用美国国家临床实验室标准委员会（NCCLS）的方法还是英国纸片法，都能实现良好的区分。

相似文献

1
Detection of extended-spectrum beta-lactamases in klebsiellae with the Oxoid combination disk method.用奥克托克斯组合纸片法检测克雷伯菌属中的超广谱β-内酰胺酶
J Clin Microbiol. 2000 Nov;38(11):4228-32. doi: 10.1128/JCM.38.11.4228-4232.2000.
2
Use of the cefepime-clavulanate ESBL Etest for detection of extended-spectrum beta-lactamases in AmpC co-producing bacteria.使用头孢吡肟-克拉维酸ESBL Etest检测产AmpC酶细菌中的超广谱β-内酰胺酶
J Infect Dev Ctries. 2009 Nov 21;4(1):24-9. doi: 10.3855/jidc.493.
3
Can results obtained with commercially available MicroScan microdilution panels serve as an indicator of beta-lactamase production among escherichia coli and Klebsiella isolates with hidden resistance to expanded-spectrum cephalosporins and aztreonam?使用市售的MicroScan微量稀释板获得的结果能否作为大肠埃希菌和克雷伯菌分离株中β-内酰胺酶产生的指标，这些分离株对广谱头孢菌素和氨曲南存在隐匿性耐药？
J Clin Microbiol. 1998 Sep;36(9):2575-9. doi: 10.1128/JCM.36.9.2575-2579.1998.
4
Cefpodoxime screening of Escherichia coli and Klebsiella spp. by Vitek for detection of organisms producing extended-spectrum beta-lactamases.使用Vitek对大肠杆菌和克雷伯菌属进行头孢泊肟筛查，以检测产超广谱β-内酰胺酶的菌株。
Diagn Microbiol Infect Dis. 2000 Dec;38(4):255-7. doi: 10.1016/s0732-8893(00)00203-0.
5
[Prevalence of extended-spectrum beta-lactamases in nosocomial Escherichia coli and Klebsiella spp. strains isolated from blood cultures].[从血培养分离的医院内大肠杆菌和克雷伯菌属菌株中广谱β-内酰胺酶的流行情况]
Mikrobiyol Bul. 2007 Oct;41(4):579-84.
6
Antibiotic resistance and production of extended-spectrum beta-lactamases amongst Klebsiella spp. from intensive care units in Europe.欧洲重症监护病房中肺炎克雷伯菌属的抗生素耐药性及超广谱β-内酰胺酶的产生
J Antimicrob Chemother. 1996 Sep;38(3):409-24. doi: 10.1093/jac/38.3.409.
7
Extended-spectrum beta-lactamase-mediated resistance among bacterial isolates recovered from ocular infections.从眼部感染分离的细菌中发现的超广谱β-内酰胺酶介导的耐药性。
Ophthalmic Res. 2012;47(1):52-6. doi: 10.1159/000322807. Epub 2011 Jun 29.
8
Characterization of clinical isolates of Klebsiella pneumoniae from 19 laboratories using the National Committee for Clinical Laboratory Standards extended-spectrum beta-lactamase detection methods.使用美国国家临床实验室标准委员会的超广谱β-内酰胺酶检测方法对来自19个实验室的肺炎克雷伯菌临床分离株进行鉴定。
J Clin Microbiol. 2001 Aug;39(8):2864-72. doi: 10.1128/JCM.39.8.2864-2872.2001.
9
Screening and confirmatory testing for extended spectrum beta-lactamases (ESBL) in Escherichia coli, Klebsiella pneumoniae, and Klebsiella oxytoca clinical isolates.对大肠杆菌、肺炎克雷伯菌和产酸克雷伯菌临床分离株进行超广谱β-内酰胺酶（ESBL）的筛查和确证试验。
Diagn Microbiol Infect Dis. 2000 Feb;36(2):113-7. doi: 10.1016/s0732-8893(99)00117-0.
10
Detection and reporting of organisms producing extended-spectrum beta-lactamases: survey of laboratories in Connecticut.产超广谱β-内酰胺酶微生物的检测与报告：康涅狄格州实验室调查
J Clin Microbiol. 1999 Dec;37(12):4065-70. doi: 10.1128/JCM.37.12.4065-4070.1999.

引用本文的文献

1
In Vitro Activity of Cefaclor/Beta-Lactamases Inhibitors (Clavulanic Acid and Sulbactam) Combination Against Extended-Spectrum Beta-Lactamase Producing Uropathogenic .头孢克洛/β-内酰胺酶抑制剂（克拉维酸和舒巴坦）联合用药对产超广谱β-内酰胺酶的尿路致病性病原菌的体外活性
Antibiotics (Basel). 2025 Jun 13;14(6):603. doi: 10.3390/antibiotics14060603.
2
Antimicrobial susceptibility testing profiles of ESBL-producing isolated from hospital and community adult patients in Blantyre, Malawi.从马拉维布兰太尔的医院和社区成年患者中分离出的产超广谱β-内酰胺酶菌株的药敏试验概况。
IJID Reg. 2021 Sep 6;1:47-52. doi: 10.1016/j.ijregi.2021.08.002. eCollection 2021 Dec.
3
Profile and antibiotic-resistance pattern of bacteria isolated from endotracheal secretions of mechanically ventilated patients at a tertiary care hospital.一家三级护理医院中从机械通气患者气管内分泌物分离出的细菌的特征及抗生素耐药模式。
J Educ Health Promot. 2021 May 31;10(1):195. doi: 10.4103/jehp.jehp_1517_20. eCollection 2021.
4
Successful de-escalation antibiotic therapy using cephamycins for sepsis caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia: A sequential 25-case series.使用头孢霉素成功降阶梯治疗产超广谱β-内酰胺酶肠杆菌科菌血症所致脓毒症：25例序贯病例系列研究
Open Med (Wars). 2020 Aug 7;15(1):782-786. doi: 10.1515/med-2020-0103. eCollection 2020.
5
Characterization of extended-spectrum-β-lactamase producing Klebsiella pneumoniae phage KP1801 and evaluation of therapeutic efficacy in vitro and in vivo.产超广谱β-内酰胺酶肺炎克雷伯菌噬菌体 KP1801 的特性及其在体外和体内治疗效果的评价。
Sci Rep. 2020 Jul 16;10(1):11803. doi: 10.1038/s41598-020-68702-y.
6
Association between Biofilm-Production and Antibiotic Resistance in Uropathogenic (UPEC): An In Vitro Study.尿路致病性大肠埃希菌（UPEC）生物膜形成与抗生素耐药性之间的关联：一项体外研究
Diseases. 2020 Jun 7;8(2):17. doi: 10.3390/diseases8020017.
7
Occurrence of Multidrug-resistant Uropathogens Implicated in Asymptomatic Bacteriuria in Adults with Sickle Cell Disease in Ile-Ife, Southwest Nigeria.尼日利亚西南部伊费地区镰状细胞病成人无症状菌尿症中涉及的多重耐药尿路病原体的发生情况
Oman Med J. 2020 Mar 30;35(2):e109. doi: 10.5001/omj.2020.27. eCollection 2020 Mar.
8
Is whole genome sequencing the answer for identifying bacteraemia?全基因组测序是识别菌血症的答案吗？
BMJ Case Rep. 2019 Dec 6;12(12):e231596. doi: 10.1136/bcr-2019-231596.
9
Prevalence and risk factors for multi-drug resistant Escherichia coli among poultry workers in the Federal Capital Territory, Abuja, Nigeria.尼日利亚阿布贾联邦首都特区禽类工作者中多重耐药大肠杆菌的流行情况和危险因素。
PLoS One. 2019 Nov 21;14(11):e0225379. doi: 10.1371/journal.pone.0225379. eCollection 2019.
10
Co-production of AmpC and extended spectrum beta-lactamases in cephalosporin-resistant Acinetobacter baumannii in Egypt.埃及头孢菌素耐药鲍曼不动杆菌中产 AmpC 和超广谱β-内酰胺酶的协同生产。
World J Microbiol Biotechnol. 2018 Dec 3;34(12):189. doi: 10.1007/s11274-018-2571-z.

本文引用的文献

1
Detection of extended-spectrum beta-lactamases in members of the family enterobacteriaceae: comparison of the MAST DD test, the double disc and the Etest ESBL.肠杆菌科细菌中产超广谱β-内酰胺酶的检测：MAST DD试验、双纸片法和Etest ESBL法的比较
J Antimicrob Chemother. 2000 Jun;45(6):881-5. doi: 10.1093/jac/45.6.881.
2
Antimicrobial resistance amongst Klebsiella spp. collected from intensive care units in Southern and Western Europe in 1997-1998.1997年至1998年期间从南欧和西欧重症监护病房收集的克雷伯菌属中的抗菌药物耐药性。
J Antimicrob Chemother. 2000 Feb;45(2):183-9. doi: 10.1093/jac/45.2.183.
3
Antimicrobial susceptibility testing for Klebsiella pneumoniae isolates resistant to extended-spectrum beta-lactam antibiotics.对耐超广谱β-内酰胺类抗生素的肺炎克雷伯菌分离株进行药敏试验。
J Formos Med Assoc. 1998 Oct;97(10):661-6.
4
Epidemiological typing of klebsiellae with extended-spectrum beta-lactamases from European intensive care units.来自欧洲重症监护病房的产超广谱β-内酰胺酶克雷伯菌的流行病学分型
J Antimicrob Chemother. 1998 May;41(5):527-39. doi: 10.1093/jac/41.5.527.
5
Interactions of beta-lactamases with sanfetrinem (GV 104326) compared to those with imipenem and with oral beta-lactams.与亚胺培南及口服β-内酰胺类药物相比，β-内酰胺酶与三苯甲基三唑巴坦（GV 104326）的相互作用。
Antimicrob Agents Chemother. 1998 May;42(5):1168-75. doi: 10.1128/AAC.42.5.1168.
6
Bases of variation in resistance to beta-lactams in Klebsiella oxytoca isolates hyperproducing K1 beta-lactamase.产超量K1β-内酰胺酶的产酸克雷伯菌分离株对β-内酰胺类抗生素耐药性的变异基础
J Antimicrob Chemother. 1997 Oct;40(4):533-41. doi: 10.1093/jac/40.4.533.
7
Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics.几代β-内酰胺类抗生素加速了β-内酰胺酶的进化与传播。
Clin Infect Dis. 1997 Jan;24 Suppl 1:S19-45. doi: 10.1093/clinids/24.supplement_1.s19.
8
Detection of extended-spectrum-beta-lactamase-producing members of the family Enterobacteriaceae with Vitek ESBL test.采用Vitek ESBL试验检测产超广谱β-内酰胺酶的肠杆菌科细菌成员
J Clin Microbiol. 1996 Dec;34(12):2997-3001. doi: 10.1128/jcm.34.12.2997-3001.1996.
9
Antibiotic resistance and production of extended-spectrum beta-lactamases amongst Klebsiella spp. from intensive care units in Europe.欧洲重症监护病房中肺炎克雷伯菌属的抗生素耐药性及超广谱β-内酰胺酶的产生
J Antimicrob Chemother. 1996 Sep;38(3):409-24. doi: 10.1093/jac/38.3.409.
10
Detection of extended-spectrum beta-lactamase (ESBL)-producing strains by the Etest ESBL screen.采用Etest ESBL筛选法检测产超广谱β-内酰胺酶（ESBL）菌株。
J Clin Microbiol. 1996 Aug;34(8):1880-4. doi: 10.1128/jcm.34.8.1880-1884.1996.