Horsley Kristin J, Rouleau Codie R, Garland Sheila N, Samuels Charles, Aggarwal Sandeep G, Stone James A, Arena Ross, Campbell Tavis S
Department of Psychology, McGill University, Montreal, QC, Canada.
Department of Psychology, University of Calgary, Calgary, AB, Canada.
J Behav Med. 2016 Aug;39(4):642-51. doi: 10.1007/s10865-016-9725-y. Epub 2016 Mar 5.
Insomnia symptoms (i.e., difficulty falling asleep, difficulty staying asleep, and early morning awakenings) are common among people with cardiovascular disease, and have been linked to adverse cardiovascular health outcomes. Reduced parasympathetic tone is one pathway through which risk may be conferred. The purpose of this study was to evaluate whether insomnia symptoms are associated with lower parasympathetic tone in cardiac rehabilitation patients with suspected insomnia. Participants (N = 121) completed a self-report measure of insomnia severity. 1-min heart rate recovery (HRR), an index of parasympathetic tone, was obtained during a maximal exercise test. Difficulty falling asleep, but not difficulty staying asleep or early awakenings, was associated with attenuated 1-min HRR. When analyses were restricted to participants with moderate and severe insomnia severity (n = 51), the strength of this association increased. In a sample of cardiac rehabilitation patients with insomnia, only the symptom of difficulty falling asleep was associated with lower parasympathetic tone, suggesting that individual insomnia symptoms may show specificity in their associations with physiological mechanisms.
失眠症状（即入睡困难、睡眠维持困难和早醒）在心血管疾病患者中很常见，并且与不良心血管健康结局相关。副交感神经张力降低是一种可能导致风险的途径。本研究的目的是评估失眠症状是否与疑似失眠的心脏康复患者较低的副交感神经张力相关。参与者（N = 121）完成了一项失眠严重程度的自我报告测量。在最大运动试验期间获得了1分钟心率恢复（HRR），这是副交感神经张力的一个指标。入睡困难与1分钟HRR减弱相关，但睡眠维持困难或早醒则不然。当分析仅限于中度和重度失眠严重程度的参与者（n = 51）时，这种关联的强度增加。在一组患有失眠的心脏康复患者样本中，只有入睡困难症状与较低的副交感神经张力相关，这表明个体失眠症状在与生理机制的关联中可能具有特异性。
