Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York.
Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York; Laser & Skin Surgery Center of New York, New York, New York.
J Am Acad Dermatol. 2016 May;74(5):931-6. doi: 10.1016/j.jaad.2015.12.010. Epub 2016 Mar 3.
Laser therapy in patients with skin of color is associated with an increased rate of complications. The 755-nm picosecond laser with the diffractive lens array (DLA) has been used for the treatment of scars, striae, and rejuvenation. By delivering high energy to focused areas, the DLA minimizes complications.
This study explores the adverse events associated with treatment with the 755-nm picosecond laser with DLA in individuals with Fitzpatrick skin type IV to VI.
A retrospective chart review of patients treated with the 755-nm picosecond laser with DLA with a standardized spot size of 6 mm, fluence of 0.71 J/cm(2), and pulse width of 750 to 850 picoseconds was performed. Standard clinical photographs were obtained before treatment and at follow-up. Treatment sites were assessed for dyspigmentation, erythema, edema, and herpetic lesions.
A total of 56 patients with Fitzpatrick skin type IV to VI, atrophic and hypertrophic scars, and pigmented lesions or striae were included. Ten patients (17.9%) were lost to follow-up. Transient adverse events, most commonly erythema and hyperpigmentation, were reported after therapy; these resolved in all cases.
Retrospective design is a limitation.
The 755-nm picosecond laser with the DLA device may be a safe therapeutic alternative for unwanted scars, pigmented lesions, and striae in patients with skin of color.
在有色人种患者中进行激光治疗会增加并发症的发生率。755nm 皮秒激光与衍射透镜阵列(DLA)已被用于治疗疤痕、妊娠纹和皮肤年轻化。通过将高能量传递到聚焦区域,DLA 最大限度地减少了并发症。
本研究探讨了在 Fitzpatrick 皮肤类型 IV 至 VI 的个体中使用 DLA 的 755nm 皮秒激光治疗相关的不良反应事件。
对接受 755nm 皮秒激光 DLA 治疗的患者进行回顾性图表分析,激光光斑大小为 6mm,能量密度为 0.71J/cm²,脉冲宽度为 750-850 皮秒。在治疗前和随访时获得标准临床照片。治疗部位评估色素减退、红斑、水肿和疱疹病变。
共纳入 56 例 Fitzpatrick 皮肤类型 IV 至 VI、萎缩性和增生性疤痕以及色素性病变或妊娠纹的患者。10 例患者(17.9%)失访。治疗后报告了短暂的不良反应事件,最常见的是红斑和色素沉着过度,所有病例均得到解决。
回顾性设计是一个局限性。
DLA 装置的 755nm 皮秒激光可能是治疗有色人种患者不良疤痕、色素性病变和妊娠纹的安全替代疗法。