原发性肺癌患者挽救性胸外科手术的当前热点话题。
Current Topics on Salvage Thoracic Surgery in Patients with Primary Lung Cancer.
作者信息
Uramoto Hidetaka
机构信息
Division of Thoracic Surgery, Saitama Cancer Center, Kita-adachi-gun, Saitama, Japan.
出版信息
Ann Thorac Cardiovasc Surg. 2016;22(2):65-8. doi: 10.5761/atcs.ra.16-00019. Epub 2016 Mar 4.
Abstract
Salvage primary tumor resection is sometimes considered for isolated local failures after definitive chemoradiation, urgent matters, such as hemoptysis (palliative intent), and in cases judged to be contraindicated for chemotherapy or definite radiation due to severe comorbidities, despite an initial clinical diagnosis of stage III or IV disease. However, salvage surgery is generally considered to be technically more difficult, with a potentially higher morbidity. This review discusses the current topics on salvage thoracic surgery such as the definition of salvage surgery and its outcome, and future perspectives.
摘要
对于在确定性放化疗后出现孤立局部失败的情况、咯血（姑息性目的）等紧急情况以及因严重合并症而被判定为化疗或确定性放疗禁忌的病例，尽管初始临床诊断为III期或IV期疾病，有时也会考虑进行挽救性原发性肿瘤切除术。然而，挽救性手术通常被认为在技术上更具难度，发病率可能更高。本综述讨论了挽救性胸外科手术的当前主题，如挽救性手术的定义及其结果，以及未来展望。
相似文献
1
Current Topics on Salvage Thoracic Surgery in Patients with Primary Lung Cancer.原发性肺癌患者挽救性胸外科手术的当前热点话题。
Ann Thorac Cardiovasc Surg. 2016;22(2):65-8. doi: 10.5761/atcs.ra.16-00019. Epub 2016 Mar 4.
2
Salvage Surgery After Definitive Chemoradiotherapy for Non-small Cell Lung Cancer.非小细胞肺癌根治性放化疗后的挽救性手术
Semin Thorac Cardiovasc Surg. 2017;29(2):233-241. doi: 10.1053/j.semtcvs.2017.02.001. Epub 2017 Feb 24.
3
Long-Term Survival after Salvage Surgery for Local Failure after Definitive Chemoradiation Therapy for Locally Advanced Non-small Cell Lung Cancer.局部晚期非小细胞肺癌根治性放化疗后局部复发行挽救性手术后的长期生存情况
Thorac Cardiovasc Surg. 2018 Mar;66(2):135-141. doi: 10.1055/s-0037-1606597. Epub 2017 Oct 9.
4
Salvage lung resection after definitive radiation (>59 Gy) for non-small cell lung cancer: surgical and oncologic outcomes.非小细胞肺癌根治性放疗（>59 Gy）后挽救性肺切除术：手术及肿瘤学结局
Ann Thorac Surg. 2008 Nov;86(5):1632-8; discussion 1638-9. doi: 10.1016/j.athoracsur.2008.07.042.
5
Trimodality vs Chemoradiation and Salvage Resection in cN2 Stage IIIA Non-Small Cell Lung Cancer.三模态治疗与放化疗联合挽救性切除术治疗 cN2 期 IIIA 期非小细胞肺癌的对比。
Semin Thorac Cardiovasc Surg. 2020 Spring;32(1):153-159. doi: 10.1053/j.semtcvs.2019.06.002. Epub 2019 Jun 17.
6
Salvage thoracic surgery in patients with lung cancer: potential indications and benefits.肺癌患者的挽救性胸外科手术：潜在适应症及益处
J Cardiothorac Surg. 2018 Jan 22;13(1):13. doi: 10.1186/s13019-018-0693-x.
7
Salvage pulmonary resection after stereotactic body radiotherapy: A feasible and safe option for local failure in selected patients.立体定向体部放疗后挽救性肺切除术：一种可行且安全的选择，适用于特定患者局部复发。
J Thorac Cardiovasc Surg. 2017 Aug;154(2):689-699. doi: 10.1016/j.jtcvs.2017.03.142. Epub 2017 Apr 14.
8
Impact of tumor size on outcomes after anatomic lung resection for stage 1A non-small cell lung cancer based on the current staging system.基于现行分期系统，肿瘤大小对 1A 期非小细胞肺癌解剖性肺切除术后结局的影响。
J Thorac Cardiovasc Surg. 2012 Feb;143(2):390-7. doi: 10.1016/j.jtcvs.2011.10.023. Epub 2011 Dec 9.
9
Salvage surgery for locoregional recurrence or persistent tumor after high dose chemoradiotherapy for locally advanced non-small cell lung cancer.局部晚期非小细胞肺癌大剂量放化疗后局部区域复发或持续性肿瘤的挽救性手术
Lung Cancer. 2016 Apr;94:108-13. doi: 10.1016/j.lungcan.2016.02.005. Epub 2016 Feb 11.
10
Pulmonary resection after curative intent radiotherapy (>59 Gy) and concurrent chemotherapy in non-small-cell lung cancer.非小细胞肺癌根治性放疗（>59 Gy）及同步化疗后的肺切除术
Ann Thorac Surg. 2004 Oct;78(4):1200-5; discussion 1206. doi: 10.1016/j.athoracsur.2004.04.085.
引用本文的文献
1
Rescue Surgery for Advanced Stage Lung Cancer: A Systematic Review.晚期肺癌的挽救性手术：一项系统综述
Thorac Cancer. 2025 Aug;16(16):e70151. doi: 10.1111/1759-7714.70151.
2
Salvage Lung Resection of Aspergilloma Mimicking Tumor Regrowth after Immune Checkpoint Inhibitor Therapy for Stage IV Squamous Cell Lung Cancer: A Case Report.免疫检查点抑制剂治疗IV期肺鳞状细胞癌后，挽救性肺切除治疗模仿肿瘤再生的曲霉菌球：一例报告
Surg Case Rep. 2025;11(1). doi: 10.70352/scrj.cr.24-0096. Epub 2025 Mar 11.
3
Anatomic lung resection after target therapy or immune checkpoint inhibitors treatment for initially unresectable advanced-staged non-small cell lung cancer: a case series.针对初始不可切除的晚期非小细胞肺癌，在接受靶向治疗或免疫检查点抑制剂治疗后进行的解剖性肺切除术：病例系列
Updates Surg. 2024 Nov 21. doi: 10.1007/s13304-024-02026-8.
4
Salvage lung resection after immunotherapy is feasible and safe.免疫治疗后挽救性肺切除术是可行且安全的。
JTCVS Open. 2024 Apr 23;20:141-150. doi: 10.1016/j.xjon.2024.03.018. eCollection 2024 Aug.
5
Multimodality Treatment and Salvage Surgery for the Treatment of Lung Cancer.肺癌的多模态治疗与挽救性手术
Cancers (Basel). 2023 Jul 12;15(14):3586. doi: 10.3390/cancers15143586.
6
Salvage surgery for advanced non-small cell lung cancer following previous immunotherapy: a retrospective study.先前免疫治疗后晚期非小细胞肺癌的挽救性手术：一项回顾性研究。
J Cardiothorac Surg. 2023 Jul 20;18(1):235. doi: 10.1186/s13019-023-02310-5.
7
Salvage Surgery for Small-Cell Lung Cancer-A Literature Review.小细胞肺癌的挽救性手术——文献综述
Cancers (Basel). 2023 Apr 11;15(8):2241. doi: 10.3390/cancers15082241.
8
Treatment of a Double Cancer Patient With Primary Inferior Vena Cava Sarcoma and Lung Adenocarcinoma: A Case Report and Literature Review.原发性下腔静脉肉瘤合并肺腺癌双癌患者的治疗：病例报告及文献综述
Front Surg. 2022 Apr 6;9:852757. doi: 10.3389/fsurg.2022.852757. eCollection 2022.
9
Results of emergency salvage lung resection after chemo- and/or radiotherapy among patients with lung cancer.肺癌患者放化疗后行急诊抢救性肺切除术的结果。
Interact Cardiovasc Thorac Surg. 2022 Jun 15;35(1). doi: 10.1093/icvts/ivac043.
10
Role of Surgical Intervention in Unresectable Non-Small Cell Lung Cancer.手术干预在不可切除的非小细胞肺癌中的作用
J Clin Med. 2020 Nov 29;9(12):3881. doi: 10.3390/jcm9123881.
本文引用的文献
1
[STRATEGY FOR THE TREATMENT OF UNRESECTABLE LUNG CANCER].
Nihon Geka Gakkai Zasshi. 2015 Nov;116(6):384-8.
2
Salvage surgery for local recurrence after carbon ion radiotherapy for patients with lung cancer.肺癌患者碳离子放疗后局部复发的挽救性手术
Eur J Cardiothorac Surg. 2016 May;49(5):1503-9. doi: 10.1093/ejcts/ezv348. Epub 2015 Oct 14.
3
Long-Term Outcomes of Lobectomy for Non-Small Cell Lung Cancer After Definitive Radiation Treatment.根治性放疗后非小细胞肺癌肺叶切除术的长期疗效
Ann Thorac Surg. 2015 Jun;99(6):1914-20. doi: 10.1016/j.athoracsur.2015.01.064. Epub 2015 Apr 15.
4
The 30-day mortality and hospital mortality after chest surgery described in the annual reports published by the Japanese Association for Thoracic and Cardiovascular Surgery.日本胸心血管外科学会发布的年度报告中所描述的胸外科手术后30天死亡率和医院死亡率。
Gen Thorac Cardiovasc Surg. 2015 May;63(5):279-83. doi: 10.1007/s11748-015-0524-0. Epub 2015 Feb 6.
5
The long-term outcomes of induction chemoradiotherapy followed by surgery for locally advanced non-small cell lung cancer.局部晚期非小细胞肺癌诱导放化疗后手术的长期疗效。
Case Rep Oncol. 2014 Oct 23;7(3):700-10. doi: 10.1159/000368598. eCollection 2014 Sep.
6
Salvage thoracic surgery in patients with primary lung cancer.肺癌患者的挽救性胸部手术。
Lung Cancer. 2014 May;84(2):151-5. doi: 10.1016/j.lungcan.2014.02.004. Epub 2014 Feb 16.
7
Treatment of stage III non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.Ⅲ期非小细胞肺癌的治疗：肺癌的诊断与管理，第 3 版：美国胸科学会循证临床实践指南。
Chest. 2013 May;143(5 Suppl):e314S-e340S. doi: 10.1378/chest.12-2360.
8
Pulmonary resections following prior definitive chemoradiation therapy are associated with acceptable survival.根治性放化疗后进行肺切除术与可接受的生存相关。
Eur J Cardiothorac Surg. 2013 Jul;44(1):e66-70. doi: 10.1093/ejcts/ezt184. Epub 2013 Apr 4.
9
Outcome of strict patient selection for surgical treatment of hepatic and pulmonary metastases from colorectal cancer.严格选择手术治疗结直肠癌肝肺转移患者的结果。
Dis Colon Rectum. 2013 Jan;56(1):43-50. doi: 10.1097/DCR.0b013e3182739f5e.
10
Salvage esophagectomy for locoregional failure after chemoradiotherapy in patients with advanced esophageal cancer.放化疗后局部区域复发的晚期食管癌患者行挽救性食管切除术。
Ann Thorac Surg. 2012 Dec;94(6):1862-8. doi: 10.1016/j.athoracsur.2012.07.042. Epub 2012 Sep 7.
Zotero 插件