Goebels Susanne, Pattmöller Max, Eppig Timo, Cayless Alan, Seitz Berthold, Langenbucher Achim
From the Department of Ophthalmology (Goebels, Pattmöller, Seitz), Saarland University Medical Center, Homburg, Germany; Experimental Ophthalmology (Eppig, Langenbucher), Saarland University, Homburg, Germany; Department of Physical Sciences (Cayless), Open University, Milton Keynes, United Kingdom.
From the Department of Ophthalmology (Goebels, Pattmöller, Seitz), Saarland University Medical Center, Homburg, Germany; Experimental Ophthalmology (Eppig, Langenbucher), Saarland University, Homburg, Germany; Department of Physical Sciences (Cayless), Open University, Milton Keynes, United Kingdom.
J Cataract Refract Surg. 2015 Nov;41(11):2387-93. doi: 10.1016/j.jcrs.2015.05.028.
Accurate biometry is an obligatory preoperative measurement for refractive surgery as well as cataract surgery. A new device based on partial coherence interferometry was compared with 2 currently used biometry devices.
Department of Ophthalmology, Saarland University Medical Center, Homburg, Germany.
Prospective case series.
Eyes of cataract patients were examined with a functional prototype of the new optical low-coherence reflectometry (OLCR) biometer OA-2000, the standard OLCR biometer Lenstar, and the partial coherence interferometry (PCI) biometer IOLMaster. The results were compared using a Wilcoxon-Mann-Whitney U test and Pearson correlation calculations.
A total of 138 eyes of 74 cataract patients were examined. Pearson correlation showed excellent correlation for axial length, anterior chamber depth and keratometry among the 3 devices tested. The highest correlation was found between standard OLCR biometer and PCI biometer for AL, R1, and R2 (r = 1.0, r = 0.936, r = 0.952, respectively; all P ≤ .001). For anterior chamber depth (ACD), the highest correlation was found between the standard OLCR biometer and the new OLCR biometer (r = 0.943; P ≤ .001). The mean values of AL/ACD/R1/R2 differed very little, but the differences were significant (all P ≤ .05) (new OLCR biometer 23.31/3.21/7.74/7.64 mm; standard OLCR biometer 23.30/3.13/7.80/7.60 mm; PCI biometer 23.37/3.00/7.78/7.6 mm).
Compared with other clinical instruments, the new OLCR biometer generated the most accurate results. Differences especially in measurement of axial length were statistically but not clinically significant. The new OLCR biometer yielded results that correlated very well with the values of the PCI biometer and standard OLCR biometer.
None of the authors has a financial or proprietary interest in any material or method mentioned.
准确的生物测量是屈光手术和白内障手术术前必需的测量项目。将一种基于部分相干干涉测量法的新设备与2种目前使用的生物测量设备进行比较。
德国洪堡萨尔州立大学医学中心眼科。
前瞻性病例系列。
使用新型光学低相干反射测量法（OLCR）生物测量仪OA - 2000的功能原型、标准OLCR生物测量仪Lenstar和部分相干干涉测量法（PCI）生物测量仪IOLMaster对白内障患者的眼睛进行检查。使用Wilcoxon - Mann - Whitney U检验和Pearson相关性计算对结果进行比较。
共检查了74例白内障患者的138只眼睛。Pearson相关性显示，在测试的3种设备之间，眼轴长度、前房深度和角膜曲率测量结果具有极好的相关性。在眼轴长度（AL）、R1和R2方面，标准OLCR生物测量仪与PCI生物测量仪之间的相关性最高（分别为r = 1.0、r = 0.936、r = 0.952；所有P≤0.001）。对于前房深度（ACD），标准OLCR生物测量仪与新型OLCR生物测量仪之间的相关性最高（r = 0.943；P≤0.001）。AL/ACD/R1/R2的平均值差异很小，但差异具有统计学意义（所有P≤0.05）（新型OLCR生物测量仪为23.31/3.21/7.74/7.64mm；标准OLCR生物测量仪为23.30/3.13/7.80/7.60mm；PCI生物测量仪为23.37/3.00/7.78/7.6mm）。
与其他临床仪器相比，新型OLCR生物测量仪产生的结果最准确。特别是在眼轴长度测量方面的差异具有统计学意义，但无临床意义。新型OLCR生物测量仪得出的结果与PCI生物测量仪和标准OLCR生物测量仪的值相关性非常好。
作者均未对文中提及的任何材料或方法拥有财务或专利权益。
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