基于部分相干干涉测量法的新型生物测量仪与基于光学低相干反射测量法的经过验证的生物测量仪之间的测量一致性。

Measurement agreement between a new biometer based on partial coherence interferometry and a validated biometer based on optical low-coherence reflectometry.

作者信息

Li Junhua, Chen Hao, Savini Giacomo, Lu Weicong, Yu Xinxin, Bao Fangjun, Wang Qinmei, Huang Jinhai

机构信息

From the School of Ophthalmology and Optometry (Li, Chen, Lu, Yu, Bao, Wang, Huang), Wenzhou Medical University, Wenzhou, Zhejiang, and the Key Laboratory of Vision Science (Li, Chen, Lu, Yu, Bao, Wang, Huang), Ministry of Health, P.R. China, Wenzhou, Zhejiang, China G.B. Bietti Foundation IRCCS (Savini), Rome, Italy.

出版信息

J Cataract Refract Surg. 2016 Jan;42(1):68-75. doi: 10.1016/j.jcrs.2015.05.042.

DOI:10.1016/j.jcrs.2015.05.042

PMID:26948780

Abstract

PURPOSE

To evaluate the agreement of ocular measurements obtained with a new optical biometer (AL-Scan) and a previously validated optical biometer (Lenstar).

SETTING

Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

DESIGN

Prospective observational cross-sectional study.

METHODS

For a comprehensive comparison between the partial coherence interferometry (PCI) device and the optical low-coherence reflectometry (OLCR) device, the axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, mean keratometry (K), astigmatism, white-to-white (WTW), and pupil diameter were measured 3 times per device in eyes with cataract. The sequence of the device was in random order. The mean values were compared and 95% limits of agreement (LoA) were assessed.

RESULTS

Ninety-two eyes of 92 cataract patients were included. Bland-Altman analysis showed excellent agreement between the PCI device and the OLCR device for AL, CCT, ACD and aqueous depth measurements with narrow 95% LoA (-0.05 to 0.06 mm, -13.39 to 15.61 μm, -0.11 to 0.10 mm, and -0.12 to 0.10 mm, respectively), and the P values were more than 0.05. The mean K, astigmatism, and WTW values provided by the PCI device were in good agreement with the OLCR device, although statistically significant differences were detected. A major difference was observed in the pupil diameter measurement, with a 95% LoA of -0.73 to 1.21 mm.

CONCLUSIONS

The PCI device biometer provided ocular measurements similar to those provided by the OLCR device for most parameters, especially for AL, CCT, and ACD. The pupil diameter values obtained with the PCI device were in poor agreement with the OLCR device, and these measurements should be interpreted with necessary adjustment.

FINANCIAL DISCLOSURE

None of the authors has a proprietary or financial interest in any material or method mentioned.

摘要

目的

评估使用新型光学生物测量仪（AL-Scan）和先前经验证的光学生物测量仪（Lenstar）所获得的眼部测量结果的一致性。

设置

中国浙江省温州市温州医科大学附属眼视光医院。

设计

前瞻性观察性横断面研究。

方法

为了全面比较部分相干干涉测量法（PCI）设备和光学低相干反射测量法（OLCR）设备，对白内障患者的眼睛，每种设备轴向长度（AL）、中央角膜厚度（CCT）、前房深度（ACD）、房水深度、平均角膜曲率（K）、散光、白到白（WTW）和瞳孔直径各测量3次。设备测量顺序随机。比较平均值并评估95%一致性界限（LoA）。

结果

纳入92例白内障患者的92只眼。Bland-Altman分析显示，PCI设备和OLCR设备在测量AL、CCT、ACD和房水深度方面一致性良好，95% LoA较窄（分别为-0.05至0.06 mm、-13.39至15.61μm、-0.11至0.10 mm和-0.12至0.10 mm），P值均大于0.05。PCI设备提供的平均K、散光和WTW值与OLCR设备一致性良好，尽管检测到有统计学显著差异。瞳孔直径测量中观察到较大差异，95% LoA为-0.73至1.21 mm。