角膜黄色瘤合并多发性内分泌肿瘤1型：一例临床病理病例报告及文献复习
Corneal xanthogranuloma in association with multiple endocrine neoplasia 1: A clinicopathologic case report and review of the literature.
作者信息
Alkatan Hind M, Al-Rajhi Ali A
机构信息
Pathology & laboratory Medicine Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; Ophthalmology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Alfaisal University, Riyadh, Saudi Arabia; Al-Magrabi Hospital, Riyadh, Saudi Arabia.
出版信息
Saudi J Ophthalmol. 2016 Jan-Mar;30(1):49-52. doi: 10.1016/j.sjopt.2015.11.006. Epub 2015 Nov 25.
Juvenile xanthogranuloma (JXG) is a benign inflammatory condition of uncertain pathogenesis. It is characterized by skin and ocular involvement - typically in the iris - in children. It has been reported in older age groups and has been also observed to involve other ocular structures such as the cornea and conjunctiva. In this case report, we are presenting an extensive right eye corneal lesion in a 43-year old male which showed the typical histopathological feature of JXG and in association with multiple endocrine neoplasia (type 1). Similar cases in the English-language literature have been also reviewed.
青少年黄色肉芽肿（JXG）是一种发病机制不明的良性炎症性疾病。其特征为儿童期皮肤和眼部受累，典型表现为虹膜受累。在老年人群中也有报道，并且还观察到其累及其他眼部结构，如角膜和结膜。在本病例报告中，我们呈现了一名43岁男性右眼广泛的角膜病变，该病变显示出JXG的典型组织病理学特征，并与多发性内分泌肿瘤（1型）相关。我们还回顾了英文文献中的类似病例。
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