Thakur M, Vaishnavi C, Ganguly N K, Kaur S, Kumar B
Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Lepr. 1989 Oct;61(4):437-41.
12 untreated lepromatous leprosy patients were screened for primary dapsone resistance by the uptake of labelled thymidine by macrophage resident M. leprae. There were found to harbour primary dapsone resistant strains of M. leprae and another three partially resistant strains to the drug. This rapid, simple and reliable method should be used routinely to screen leprosy patients, for drug resistance.
