关于麻风病现场病例和住院病例中对砜类耐药麻风杆菌菌株的研究。
Studies on sulphone resistant strains of M. leprae in field and institutionalized cases of leprosy.
作者信息
Balakrishnan S, Seshadri P S, Neelan P N, Venkataramaniah H N, Harikrishnan S, Bhatia V N
出版信息
Lepr India. 1983 Jan;55(1):71-5.
The proportions of dapsone resistant strains of M. leprae in cases from the field and in patient institutionalized for treatment were compared. Identification of dapsone resistance was done by mouse-foot-pad experiments carried out in the Laboratory in Central Leprosy Teaching and Research Institute, Chengalpattu. A higher percentage of resistance was detected among institutional patients as compared to field cases. The distribution of M.I. ranges of M. leprae in dapsone resistant subjects was not different from that in dapsone sensitive cases.
比较了来自现场病例和住院治疗患者中耐氨苯砜麻风杆菌菌株的比例。耐氨苯砜性的鉴定是通过在金奈加尔帕图中央麻风病教学与研究所实验室进行的小鼠足垫实验完成的。与现场病例相比，住院患者中检测到的耐药百分比更高。耐氨苯砜受试者中麻风杆菌的MI范围分布与氨苯砜敏感病例中的分布没有差异。
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