Carr Alexander, Doyle Anthony J, Dalbeth Nicola, Aati Opetaia, McQueen Fiona M
1 Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand.
2 Department of Radiology, Auckland City Hospital, Auckland District Health Board, Auckland, New Zealand.
AJR Am J Roentgenol. 2016 May;206(5):1063-7. doi: 10.2214/AJR.15.15356. Epub 2016 Mar 9.
The purpose of this study was to investigate whether monosodium urate (MSU) deposits could be identified within the abdomen and axial skeleton of patients with tophaceous gout using dual-energy CT (DECT).
DECT of the abdomen, chest wall, and spine revealed extensive MSU deposits in costal cartilages and, to a lesser extent, intervertebral disks in the male patients with gout in our study. These were quantified volumetrically. However, age-matched control subjects showed similar deposits, indicating this was not a disease-specific finding. Thus, MSU deposition in the axial skeleton may be physiologic in middle-aged men.
本研究旨在探讨使用双能CT（DECT）能否在痛风石性痛风患者的腹部和中轴骨骼中识别出尿酸钠（MSU）沉积。
在我们的研究中，对男性痛风患者的腹部、胸壁和脊柱进行双能CT检查发现，肋软骨中有大量MSU沉积，在较小程度上，椎间盘也有沉积。这些沉积进行了体积定量分析。然而，年龄匹配的对照受试者也有类似的沉积，表明这不是疾病特异性表现。因此，中年男性中轴骨骼中的MSU沉积可能是生理性的。
