Demiröz P, Serbes S, Keskin K, Irmak H, Kocabalkan F
GATA, Enfeksiyon Hastaliklari ve Klinik Mikrobiyoloji Anabilim Dali, Başkanliği.
Mikrobiyol Bul. 1989 Jan;23(1):80-4.
Lyme disease, which is caused by the tick-borne spirochete Borrelia burgdorferi, usually begins with a characteristic skin lesion erythema chronicum migrans (ECM), that may be followed by neurological or cardiac abnormalities and is accompanied by malaise, fatigue, fever, myalgia, headache, lymphadenopathy and is often followed by arthritis. The disease takes its name from Lyme, Connecticut, where the full spectrum of illness was first described in 1975. It is known to be a multisystemic infectious disease. Because culture and direct visualisation of spirochetes are often negative in Lyme disease, serological testing has been the only practical laboratory aid in diagnosis and primarily clinical findings.
莱姆病由蜱传播的螺旋体伯氏疏螺旋体引起，通常始于特征性皮肤病变慢性游走性红斑（ECM），随后可能出现神经或心脏异常，并伴有不适、疲劳、发热、肌痛、头痛、淋巴结病，且常继以关节炎。该病得名于美国康涅狄格州的莱姆镇，1975年在那里首次描述了该病的全貌。它是一种已知的多系统感染性疾病。由于莱姆病中螺旋体的培养和直接观察往往呈阴性，血清学检测一直是诊断中唯一实用的实验室辅助手段，主要依据临床症状。
