Ricco R, Liso V, Specchia G, Pavone V, Marzano N, Lettini T, Pesce Delfino V, Pennella A
Institute of Pathological Anatomy, Haematology, University of Bari, Italy.
Pathol Res Pract. 1989 Nov;185(5):715-8. doi: 10.1016/S0344-0338(89)80224-9.
A morphometric study of the nuclear and cytoplasmic shape of a blastic population in a case of HM-A.L.L. was performed by comparing the two differently shaped populations with and without HM configuration. The results obtained using analytical size-independent parameters created by the S.A.M. work-station enable us to characterize the shape of both blastic cell populations quantitatively, and strongly suggest the existence of shape modulation from one cellular type toward the other. Thus a possible sequence from blastic cells (having regular, rather round nuclei) to HM cells (characterized by high distortion of both nucleus and cytoplasm) was proposed.
对一例HM - A.L.L. 患者的母细胞群体的细胞核和细胞质形态进行了形态计量学研究，通过比较具有和不具有HM构型的两种不同形状的群体来进行。使用S.A.M. 工作站创建的与大小无关的分析参数获得的结果，使我们能够定量地表征两种母细胞群体的形状，并有力地表明存在从一种细胞类型向另一种细胞类型的形状调节。因此，提出了从母细胞（具有规则的、相当圆的细胞核）到HM细胞（以细胞核和细胞质的高度变形为特征）的可能序列。
