二氧化硅纳米粒子对枯草芽孢杆菌 IMV B-7023 抗氧化潜力的影响。

Department of Microbiological Processes on Solid Surfaces, Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad. Zabolotny St., Kyiv, MSP, D03680, Ukraine.

Nanoscale Res Lett. 2016 Dec;11(1):139. doi: 10.1186/s11671-016-1348-2. Epub 2016 Mar 12.

It was found that if introduced into a nutrient medium of 0.05-1 g/L nano-SiO2, the oxidant activity (OA) of the culture medium (CM) of bacilli increased by 43.2-60.1 % and the antioxidant activity (AA) decreased by 4.5-11.8 %. SiO2 nanoparticles had different effects on antiradical activity (ARA) of the CM of Bacillus subtilis IMV B-7023. In particular, nano-SiO2 had no significant effect on the ability of the CM of bacilli to inactivate the 2.2-diphenyl-1-picrylhydrazyl (DPPH·) free radical. However, for the content of the nanomaterial of 0.01-1 g/L decreased hydroxyl radical scavenging in the CM of B. subtilis IMV B-7023 on 7.2-17.6 % compared with a control. Low doses of silica nanoparticles stimulated the reducing power of the CM of bacteria and then highly suppressed it.

研究发现，纳米 SiO2 加入到浓度为 0.05-1g/L 的培养基中时，杆菌培养基（CM）的氧化剂活性（OA）提高了 43.2-60.1%，抗氧化活性（AA）降低了 4.5-11.8%。SiO2 纳米粒子对枯草芽孢杆菌 IMV B-7023 的 CM 的抗自由基活性（ARA）有不同的影响。特别是纳米 SiO2 对 CM 灭活 2.2-二苯基-1-苦肼基自由基的能力没有显著影响。然而，对于 0.01-1g/L 的纳米材料含量，与对照组相比，枯草芽孢杆菌 IMV B-7023 的 CM 中羟基自由基的清除率降低了 7.2-17.6%。低剂量的二氧化硅纳米粒子刺激了细菌 CM 的还原能力，然后强烈抑制了它。