采用三光束多普勒光学相干断层扫描技术测量视网膜总血流量。
Total retinal blood flow measurement by three beam Doppler optical coherence tomography.
作者信息
Haindl Richard, Trasischker Wolfgang, Wartak Andreas, Baumann Bernhard, Pircher Michael, Hitzenberger Christoph K
机构信息
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria;
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria; Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, USA.
出版信息
Biomed Opt Express. 2016 Jan 6;7(2):287-301. doi: 10.1364/BOE.7.000287. eCollection 2016 Feb 1.
Abstract
We present measurements of total retinal blood flow in healthy volunteers using a three beam Doppler optical coherence tomography (D-OCT) technique. This technology has the advantage of a precise determination of the flow vector without the use of any a-priori information on the vessel geometry. Circular D-OCT scans around the optic disc were recorded and venous as well as arterial total blood flow was determined and compared for each subject. The reproducibility of the method was assessed in 6 subjects by repeated measurements. Only small deviations of around 6% between the measurements were found which indicates the high precision of the proposed method.
摘要
我们使用三光束多普勒光学相干断层扫描（D-OCT）技术对健康志愿者的视网膜总血流量进行了测量。该技术的优点是无需任何关于血管几何形状的先验信息就能精确确定血流矢量。记录了围绕视盘的圆形D-OCT扫描，并确定了每个受试者的静脉和动脉总血流量并进行比较。通过重复测量对6名受试者评估了该方法的可重复性。测量之间仅发现约6%的小偏差，这表明所提出方法的高精度。
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