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本文引用的文献

1
Three-beam Doppler optical coherence tomography using a facet prism telescope and MEMS mirror for improved transversal resolution.使用小面棱镜望远镜和微机电系统(MEMS)镜的三光束多普勒光学相干断层扫描技术,用于提高横向分辨率。
J Mod Opt. 2015;62(21):1781-1788. doi: 10.1080/09500340.2014.983569.
2
Blood flow velocity vector field reconstruction from dual-beam bidirectional Doppler OCT measurements in retinal veins.基于视网膜静脉双光束双向多普勒光学相干断层扫描测量的血流速度矢量场重建
Biomed Opt Express. 2015 Apr 6;6(5):1599-615. doi: 10.1364/BOE.6.001599. eCollection 2015 May 1.
3
Variability and repeatability of quantitative, Fourier-domain optical coherence tomography Doppler blood flow in young and elderly healthy subjects.年轻和老年健康受试者定量傅里叶域光学相干断层扫描多普勒血流的变异性和可重复性。
Invest Ophthalmol Vis Sci. 2014 Oct 21;55(12):7716-25. doi: 10.1167/iovs.14-14430.
4
Doppler optical coherence tomography.多普勒光学相干断层扫描
Prog Retin Eye Res. 2014 Jul;41(100):26-43. doi: 10.1016/j.preteyeres.2014.03.004. Epub 2014 Apr 3.
5
Measurement of the total retinal blood flow using dual beam Fourier-domain Doppler optical coherence tomography with orthogonal detection planes.使用具有正交检测平面的双光束傅里叶域多普勒光学相干断层扫描技术测量视网膜总血流量。
Biomed Opt Express. 2014 Jan 28;5(2):630-42. doi: 10.1364/BOE.5.000630. eCollection 2014 Feb 1.
6
Orientation-independent rapid pulsatile flow measurement using dual-angle Doppler OCT.使用双角度多普勒光学相干断层扫描进行与方向无关的快速搏动血流测量。
Biomed Opt Express. 2014 Jan 15;5(2):499-514. doi: 10.1364/BOE.5.000499. eCollection 2014 Feb 1.
7
Retinal blood flow in glaucomatous eyes with single-hemifield damage.单眼视野损害青光眼眼视网膜血流。
Ophthalmology. 2014 Mar;121(3):750-8. doi: 10.1016/j.ophtha.2013.10.022. Epub 2013 Nov 28.
8
In vitro and in vivo three-dimensional velocity vector measurement by three-beam spectral-domain Doppler optical coherence tomography.采用三束谱域多普勒光学相干断层成像术进行体外和体内三维速度矢量测量。
J Biomed Opt. 2013 Nov;18(11):116010. doi: 10.1117/1.JBO.18.11.116010.
9
Ocular perfusion pressure in glaucoma.青光眼的眼内灌注压。
Acta Ophthalmol. 2014 Jun;92(4):e252-66. doi: 10.1111/aos.12298. Epub 2013 Nov 18.
10
Dove prism based rotating dual beam bidirectional Doppler OCT.基于 Dove 棱镜的旋转双光束双向多普勒光学相干断层扫描。
Biomed Opt Express. 2013 Jun 24;4(7):1188-203. doi: 10.1364/BOE.4.001188. Print 2013 Jul 1.

采用三光束多普勒光学相干断层扫描技术测量视网膜总血流量。

Total retinal blood flow measurement by three beam Doppler optical coherence tomography.

作者信息

Haindl Richard, Trasischker Wolfgang, Wartak Andreas, Baumann Bernhard, Pircher Michael, Hitzenberger Christoph K

机构信息

Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria;

Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria; Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, USA.

出版信息

Biomed Opt Express. 2016 Jan 6;7(2):287-301. doi: 10.1364/BOE.7.000287. eCollection 2016 Feb 1.

DOI:10.1364/BOE.7.000287
PMID:26977340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4771449/
Abstract

We present measurements of total retinal blood flow in healthy volunteers using a three beam Doppler optical coherence tomography (D-OCT) technique. This technology has the advantage of a precise determination of the flow vector without the use of any a-priori information on the vessel geometry. Circular D-OCT scans around the optic disc were recorded and venous as well as arterial total blood flow was determined and compared for each subject. The reproducibility of the method was assessed in 6 subjects by repeated measurements. Only small deviations of around 6% between the measurements were found which indicates the high precision of the proposed method.

摘要

我们使用三光束多普勒光学相干断层扫描(D-OCT)技术对健康志愿者的视网膜总血流量进行了测量。该技术的优点是无需任何关于血管几何形状的先验信息就能精确确定血流矢量。记录了围绕视盘的圆形D-OCT扫描,并确定了每个受试者的静脉和动脉总血流量并进行比较。通过重复测量对6名受试者评估了该方法的可重复性。测量之间仅发现约6%的小偏差,这表明所提出方法的高精度。