Ingber Susan Z, Pohl Hana R
Agency for Toxic Substances and Disease Registry, 1600 Clifton Rd, Mailstop F-57, Atlanta, GA 30333, United States.
Data Brief. 2016 Jan 2;6:445-55. doi: 10.1016/j.dib.2015.12.036. eCollection 2016 Mar.
The authors reviewed human data related to motor development following exposure to a subset of chemicals thoroughly reviewed in Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles and Addenda. The resulting dataset includes the following variables and confounders: chemical name, exposure route, exposure duration and frequency, study design, cohort name and/or geographic location, sex of cohort subjects, NOAEL, and LOAEL. This data summary can help validate motor development outcomes observed in animal exposure studies; it can also aid in determining whether these outcomes and corresponding exposure windows are relevant to humans.
作者回顾了与接触美国有毒物质和疾病登记署（ATSDR）毒理学概况及补遗中全面审查的一部分化学物质后运动发育相关的人体数据。所得数据集包括以下变量和混杂因素：化学物质名称、接触途径、接触持续时间和频率、研究设计、队列名称和/或地理位置、队列受试者的性别、未观察到有害作用的剂量（NOAEL）和观察到有害作用的最低剂量（LOAEL）。这一数据总结有助于验证在动物接触研究中观察到的运动发育结果；它还可以帮助确定这些结果及相应的接触窗口期是否与人类相关。
