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复原力:一种针对精神疾病的心理生物学概念。

Resilience: A psychobiological construct for psychiatric disorders.

作者信息

Shrivastava Amresh, Desousa Avinash

机构信息

Department of Psychiatry, The Western University, Lawson Health Research Institute, London, Ontario N6C 0A7, Canada.

Department of Psychiatry, Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India.

出版信息

Indian J Psychiatry. 2016 Jan-Mar;58(1):38-43. doi: 10.4103/0019-5545.174365.

Abstract

Understanding of psychopathology of mental disorder is evolving, particularly with availability of newer insight from the field of genetics, epigenetics, social, and environmental pathology. It is now becoming clear how biological factors are contributing to development of an illness in the face of a number of psychosocial factors. Resilience is a psychobiological factor which determines individual's response to adverse life events. Resilience is a human capacity to adapt swiftly and successfully to stressful/traumatic events and manage to revert to a positive state. It is fundamental for growth of positive psychology which deals with satisfaction, adaptability, contentment, and optimism in people's life. Of late, there has been a paradigm shift in the understanding of resilience in context of stress risk vulnerability dimension. It is a neurobiological construct with significant neurobehavioral and emotional features which plays important role in deconstructing mechanism of biopsychosocial model of mental disorders. Resilience is a protective factor against development of mental disorder and a risk factor for a number of clinical conditions, e.g. suicide. Available information from scientific studies points out that resilience is modifiable factor which opens up avenues for a number of newer psychosocial as well as biological therapies. Early identification of vulnerable candidates and effectiveness of resilience-based intervention may offer more clarity in possibility of prevention. Future research may be crucial for preventive psychiatry. In this study, we aim to examine whether resilience is a psychopathological construct for mental disorder.

摘要

对精神障碍心理病理学的理解正在不断发展,尤其是随着遗传学、表观遗传学、社会和环境病理学领域有了更新的见解。现在越来越清楚的是,在诸多心理社会因素面前,生物因素是如何促成疾病发展的。复原力是一种心理生物学因素,它决定个体对不良生活事件的反应。复原力是人类迅速且成功地适应压力/创伤性事件并设法恢复到积极状态的能力。它是积极心理学发展的基础,积极心理学关注人们生活中的满意度、适应能力、满足感和乐观态度。近来,在压力风险易损性维度的背景下,对复原力的理解发生了范式转变。它是一种具有显著神经行为和情感特征的神经生物学结构,在解构精神障碍生物心理社会模型的机制中发挥着重要作用。复原力是预防精神障碍的保护因素,也是一些临床病症(如自杀)的风险因素。科学研究提供的信息指出,复原力是一个可改变的因素,这为许多新的心理社会疗法以及生物疗法开辟了道路。早期识别易损个体以及基于复原力的干预措施的有效性,可能会让预防的可能性更加清晰。未来的研究对预防精神病学可能至关重要。在本研究中,我们旨在探讨复原力是否是精神障碍的一种心理病理学结构。

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