Bolanča Željana, Goren Andy, Getaldić-Švarc Biserka, Vučić Majda, Šitum Mirna
Department of Dermatovenereology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
University of Rome ("G. Marconi"), Rome, Italy.
Dermatol Ther. 2016 Jul;29(4):233-5. doi: 10.1111/dth.12343. Epub 2016 Mar 14.
Treatment of lichen planopillaris (LPP) remains a significant challenge due to the irreversible damage inflicted on hair follicles combined with the low efficacy of existing treatments. We hypothesized that growth factors released by the use of platelet-rich plasma (PRP) may arrest the development of LPP. To test our hypothesis, we treated an LPP patient that has failed previous treatments with a new PRP regimen. Following PRP treatment and six months follow-up, the patient experienced complete regression of itching and hair shedding. To the best of our knowledge, this is the first report of successful treatment of LPP with a PRP regimen.
扁平苔藓样毛发角化病（LPP）的治疗仍然是一项重大挑战，因为毛囊会受到不可逆的损伤，且现有治疗方法疗效欠佳。我们推测，使用富含血小板血浆（PRP）释放的生长因子可能会阻止LPP的发展。为了验证我们的假设，我们采用一种新的PRP方案治疗了一名先前治疗失败的LPP患者。经过PRP治疗和六个月的随访，该患者的瘙痒和脱发症状完全消退。据我们所知，这是首例使用PRP方案成功治疗LPP的报告。
