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目标导向液体治疗在病态肥胖患者腹腔镜袖状胃切除术中的应用

Goal-Directed Fluid Therapy on Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients.

作者信息

Muñoz José Luis, Gabaldón Tanya, Miranda Elena, Berrio Diana Lorena, Ruiz-Tovar Jaime, Ronda José María, Esteve Nuria, Arroyo Antonio, Pérez Ana

机构信息

Hospital General Universitario de Elche, Elche, Alicante, Spain.

出版信息

Obes Surg. 2016 Nov;26(11):2648-2653. doi: 10.1007/s11695-016-2145-9.

Abstract

BACKGROUND

In bariatric surgery, there are no guidelines available for intraoperative fluid administration. Goal-directed fluid therapy (GDFT) is a new concept of perioperative fluid management that has been shown to improve the prognosis of patients undergoing abdominal surgery. The aim of our study is to assess the impact of the implementation of a GDFT protocol in morbidly obese patients who underwent laparoscopic sleeve gastrectomy (LSG).

METHODS

A before-after intervention study, in morbidly obese patients who underwent LSG, was conducted at the Obesity Unit of the General University Hospital Elche. Data from the GDFT implementation group (January 2014 to December 2015) were prospectively collected and compared with a preimplementation group (January 2012 to December 2013).

RESULTS

Baseline demographic and comorbidity data between the two groups of patients were similar. The length of stay in the hospital was significantly shortened in GDFT group from 4.5 to 3.44 days (p < 0.001). Intraoperative fluid administration was significantly lower in the GDFT group (1002.4 vs 1687.2 ml in preimplementation group, p < 0.001). In the postoperative period, there was a statistically significant reduction in postoperative nausea and vomiting (PONV) after GDFT implementation (48 to 14.3 %, p < 0.001).

CONCLUSIONS

Implementation of GDFT protocols can prevent intraoperative fluid overload in patients undergoing bariatric surgery. It could improve outcomes, for example decreasing PONV or even hospital stay.

摘要

背景

在减肥手术中,尚无术中液体管理的指南。目标导向液体治疗(GDFT)是围手术期液体管理的新概念,已被证明可改善接受腹部手术患者的预后。我们研究的目的是评估实施GDFT方案对接受腹腔镜袖状胃切除术(LSG)的病态肥胖患者的影响。

方法

在埃尔切大学综合医院肥胖科对接受LSG的病态肥胖患者进行了一项干预前后的研究。前瞻性收集了GDFT实施组(2014年1月至2015年12月)的数据,并与实施前组(2012年1月至2013年12月)进行比较。

结果

两组患者的基线人口统计学和合并症数据相似。GDFT组的住院时间从4.5天显著缩短至3.44天(p<0.001)。GDFT组术中液体输入量显著降低(实施前组为1687.2毫升,GDFT组为1002.4毫升,p<0.001)。在术后阶段,实施GDFT后术后恶心呕吐(PONV)有统计学显著降低(从48%降至14.3%,p<0.001)。

结论

实施GDFT方案可预防减肥手术患者术中液体过载。它可以改善预后,例如减少PONV甚至缩短住院时间。

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