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几种中国药用水果的热水提取物和胞内多糖的抗氧化能力

Antioxidant Capacities of Hot Water Extracts and Endopolysaccharides of Selected Chinese Medicinal Fruits.

作者信息

Jeong Sang Chul, Tulasi Ratna, Koyyalamudi Sundar Rao

机构信息

School of Science and Health, University of Western Sydney, Locked Bag 1797, Penrith South DC, NSW 1797, Australia.

Freshwater Bioresources Utilization Division, Nakdonggang National Institute of Biological Resources, Sangju-si 37242, Korea.

出版信息

Cancers (Basel). 2016 Mar 9;8(3):33. doi: 10.3390/cancers8030033.

DOI:10.3390/cancers8030033
PMID:27005663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4810117/
Abstract

Fruits are a rich source of antioxidants and traditional Chinese fruits have been studied for their chemopreventive and chemotherapeutic properties against cancers and other diseases. The total phenol and flavonoid contents of eleven Chinese fruits extracts were determined. Total phenolic and flavonoid contents were estimated by both the Folin-Ciocalteau and aluminium chloride methods. The antioxidant activities were evaluated by four assays: a biological assay using Saccharomyces cerevisiae, DPPH radical scavenging activity, chelating ability for ferrous ions and ferric reducing antioxidant power (FRAP). The phenols and flavonoids contents of the hot water extracts were in the range of 17.7 to 94.7 mg/g and 12.3 to 295.4 mg/g, whereas the endopolysaccharides lie in the range of 4.5 to 77.4 mg/g and 22.7 to 230.0 mg/g. Significant amounts of phenols and flavonoids were present in the majority of the fruit extracts and showed strong antioxidant activities. The antioxidant properties of the fruit extracts of Crataegus pinnatifida, Illicium verum, Ligustrum lucidum, Momordica grosvenori and Psoralea corylifolia as determined by the DPPH and FRAP methods, were significant compared to other fruit extracts. In the present study, we found that significant amounts of phenolic and flavonoid compounds were present in these fruit extracts and may contribute to in vitro antioxidant activities.

摘要

水果富含抗氧化剂,中国传统水果已针对其对癌症和其他疾病的化学预防及化疗特性进行了研究。测定了11种中国水果提取物中的总酚和黄酮含量。总酚和黄酮含量通过福林-西奥尔特法和氯化铝法进行估算。通过四种测定方法评估抗氧化活性:使用酿酒酵母的生物学测定法、DPPH自由基清除活性、对亚铁离子的螯合能力以及铁还原抗氧化能力(FRAP)。热水提取物中的酚类和黄酮类含量范围分别为17.7至94.7毫克/克和12.3至295.4毫克/克,而胞内多糖含量范围分别为4.5至77.4毫克/克和22.7至230.0毫克/克。大多数水果提取物中存在大量的酚类和黄酮类物质,并表现出较强的抗氧化活性。通过DPPH和FRAP方法测定,山楂、八角、女贞、罗汉果和补骨脂的水果提取物的抗氧化性能与其他水果提取物相比具有显著性。在本研究中,我们发现这些水果提取物中存在大量的酚类和黄酮类化合物,可能有助于体外抗氧化活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/70ac6ed22581/cancers-08-00033-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/784ca934b869/cancers-08-00033-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/e1641753e58f/cancers-08-00033-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/2a4975e44641/cancers-08-00033-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/86d376bf1a8a/cancers-08-00033-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/70ac6ed22581/cancers-08-00033-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/784ca934b869/cancers-08-00033-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/e1641753e58f/cancers-08-00033-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/2a4975e44641/cancers-08-00033-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/86d376bf1a8a/cancers-08-00033-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3c2/4810117/70ac6ed22581/cancers-08-00033-g005.jpg

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