Ao Jack, Goldblatt Fiona, Casson Robert J
South Australian Institute of Ophthalmology, University of Adelaide, Adelaide, South Australia, Australia.
Department of Rheumatology, The Repatriation General Hospital, Adelaide, South Australia, Australia.
Clin Exp Ophthalmol. 2017 Jan;45(1):73-80. doi: 10.1111/ceo.12749. Epub 2016 May 1.
Gout is a clinical disorder that is characterized by the deposition of monosodium urate crystals (MSU) in joints and tendons, usually in the presence of prolonged hyperuricaemia. Following an asymptomatic phase of hyperuricaemia, gout usually presents as acute monoarthritis followed by periods of remission and exacerbation. Conjunctival hyperaemia and subconjunctival haemorrhage exacerbated by purine intake are two of the more common manifestations that may go unrecognized. Other ocular and adnexal structures can be affected by urate crystal deposition and associated inflammation, with potentially vision-threatening consequences; however, ocular manifestations of gout are rare and may have been over-reported in the older literature, but our understanding of the clinic-pathological features of ocular urate deposits remains limited.
痛风是一种临床病症，其特征是单钠尿酸盐晶体（MSU）在关节和肌腱中沉积，通常发生在长期高尿酸血症的情况下。在高尿酸血症的无症状期之后，痛风通常表现为急性单关节炎，随后是缓解期和加重期。因嘌呤摄入而加重的结膜充血和结膜下出血是两种较常见的表现，可能未被识别。其他眼部和附属结构可受到尿酸盐晶体沉积及相关炎症的影响，可能产生威胁视力的后果；然而，痛风的眼部表现很少见，在较早的文献中可能存在过度报道的情况，但我们对眼部尿酸盐沉积的临床病理特征的了解仍然有限。
