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痛风发作会引发非动脉炎性前部缺血性视神经病变吗?

Could a Gout Attack Cause Non-Arteritic Anterior Ischaemic Optic Neuropathy?

作者信息

Karti Omer, Top Karti Dilek, Kiyat Pelin, Şak Tuncer

机构信息

Buca Seyfi Demirsoy Training and Research Hospital Department of Ophthalmology, İzmir Democracy University, İzmir, Türkiye.

Department of Neurology, Bozyaka Training and Research Hospital, İzmir, Türkiye.

出版信息

Neuroophthalmology. 2023 Jun 1;47(5-6):269-273. doi: 10.1080/01658107.2023.2212759. eCollection 2023.

Abstract

Non-arteritic anterior ischaemic optic neuropathy (NAION) is a common cause of optic neuropathy in individuals over the age of 50. While risk factors such as hypertension, diabetes, and hyperlipidaemia have been identified, recent literature suggests that new risk factors may be associated with NAION. This article reports a case of NAION that occurred concurrently with an acute gout attack in a 78-year-old male patient with no other systemic diseases. We suggest that gout may be a new potential risk factor for NAION as it has the potential to cause inflammation and vascular dysfunction, particularly during acute attacks. The case emphasises the importance of considering gout as a possible risk factor in the aetiology of NAION.

摘要

非动脉炎性前部缺血性视神经病变(NAION)是50岁以上人群视神经病变的常见原因。虽然已经确定了高血压、糖尿病和高脂血症等风险因素,但最近的文献表明,可能有新的风险因素与NAION相关。本文报告了一例78岁男性患者,在无其他全身性疾病的情况下,NAION与急性痛风发作同时发生。我们认为痛风可能是NAION的一个新的潜在风险因素,因为它有可能引起炎症和血管功能障碍,尤其是在急性发作期间。该病例强调了在NAION病因学中考虑痛风作为可能风险因素的重要性。

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