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理清眼睛与大脑之间的关系网。

Untangling the Web between Eye and Brain.

作者信息

Chen Chinfei, Bickford Martha E, Hirsch Judith A

机构信息

Boston Children's Hospital, F.M. Kirby Neurobiology Center, Harvard Medical School, 3 Blackfan Circle, Boston, MA 02115, USA.

Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, 511 South Floyd Street, Louisville, Kentucky 40292, USA.

出版信息

Cell. 2016 Mar 24;165(1):20-21. doi: 10.1016/j.cell.2016.03.010.

DOI:10.1016/j.cell.2016.03.010
PMID:27015304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6193467/
Abstract

How is the picture of the visual scene that the eye encodes represented by neural circuits in the brain? In this issue of Cell, Morgan et al. address this question by forming an ultrastructural "connectome" of the mouse's visual thalamus that depicts individual retinal afferents and every contact these form with target relay cells.

摘要

眼睛编码的视觉场景图像是如何由大脑中的神经回路来呈现的呢?在本期《细胞》杂志中,摩根等人通过构建小鼠视觉丘脑的超微结构“连接组”来解决这个问题,该连接组描绘了单个视网膜传入神经以及它们与目标中继细胞形成的每一个接触点。

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本文引用的文献

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The Fuzzy Logic of Network Connectivity in Mouse Visual Thalamus.小鼠视觉丘脑网络连接的模糊逻辑
Cell. 2016 Mar 24;165(1):192-206. doi: 10.1016/j.cell.2016.02.033.
2
Retinal and Tectal "Driver-Like" Inputs Converge in the Shell of the Mouse Dorsal Lateral Geniculate Nucleus.视网膜和顶盖“驱动样”输入汇聚于小鼠背外侧膝状核的壳区。
J Neurosci. 2015 Jul 22;35(29):10523-34. doi: 10.1523/JNEUROSCI.3375-14.2015.
3
Statistical wiring of thalamic receptive fields optimizes spatial sampling of the retinal image.丘脑感受野的统计布线优化了视网膜图像的空间采样。
Neuron. 2014 Feb 19;81(4):943-956. doi: 10.1016/j.neuron.2013.12.014.
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Diverse visual features encoded in mouse lateral geniculate nucleus.在小鼠外侧膝状体中编码的多样化视觉特征。
J Neurosci. 2013 Mar 13;33(11):4642-56. doi: 10.1523/JNEUROSCI.5187-12.2013.
5
Development of single retinofugal axon arbors in normal and β2 knock-out mice.正常和β2 敲除小鼠中单条视网膜传出轴突树突的发育。
J Neurosci. 2011 Mar 2;31(9):3384-99. doi: 10.1523/JNEUROSCI.4899-10.2011.
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Resolving single cone inputs to visual receptive fields.解析单个视锥细胞输入至视觉感受野的过程。
Nat Neurosci. 2009 Aug;12(8):967-9. doi: 10.1038/nn.2352. Epub 2009 Jun 28.
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Parallel processing strategies of the primate visual system.灵长类视觉系统的并行处理策略。
Nat Rev Neurosci. 2009 May;10(5):360-72. doi: 10.1038/nrn2619. Epub 2009 Apr 8.
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Distinct roles for spontaneous and visual activity in remodeling of the retinogeniculate synapse.自发活动和视觉活动在视网膜膝状体突触重塑中的不同作用。
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The functional organization of local circuits in visual cortex: insights from the study of tree shrew striate cortex.视觉皮层局部回路的功能组织:来自树鼩纹状皮层研究的见解
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