极端微生物与生物技术：当前的应用与前景
Extremophiles and biotechnology: current uses and prospects.
作者信息
Coker James A
机构信息
Department of Biotechnology, University of Maryland, Adelphi, MD, USA.
出版信息
F1000Res. 2016 Mar 24;5. doi: 10.12688/f1000research.7432.1. eCollection 2016.
Abstract
Biotechnology has almost unlimited potential to change our lives in very exciting ways. Many of the chemical reactions that produce these products can be fully optimized by performing them at extremes of temperature, pressure, salinity, and pH for efficient and cost-effective outcomes. Fortunately, there are many organisms (extremophiles) that thrive in extreme environments found in nature and offer an excellent source of replacement enzymes in lieu of mesophilic ones currently used in these processes. In this review, I discuss the current uses and some potential new applications of extremophiles and their products, including enzymes, in biotechnology.
摘要
生物技术有着几乎无限的潜力，能以非常令人兴奋的方式改变我们的生活。许多产生这些产品的化学反应可以通过在极端的温度、压力、盐度和pH值条件下进行，从而得到充分优化，以实现高效且具成本效益的结果。幸运的是，有许多生物体（嗜极生物）在自然界中极端环境中茁壮成长，它们可提供优良的替代酶源，以取代目前在这些过程中使用的嗜温酶。在这篇综述中，我讨论了嗜极生物及其产物（包括酶）在生物技术中的当前用途和一些潜在的新应用。
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