Yang Li'an, Chen Zhenqi, Zhang Xiaoyue
Department of Orthodontics, School of Stomatology, Shanghai Ninth People's Hospital, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University.
J Oral Sci. 2016;58(1):109-15. doi: 10.2334/josnusd.58.109.
Our study aimed to examine facial asymmetry in patients with unilateral cleft lip and palates (UCLP) using cone-beam computed tomography (CBCT) and explore the factors responsible for lower facial asymmetry in these individuals. The experimental group included 21 adolescent patients with non-syndromic UCLP while the control group comprised 14 patients without any facial cleft defects. The maxillofacial regions of the patients in the two groups were scanned using CBCT, and the Mimics 10.01 software was used to analyze the images. Multiple linear stepwise regression analysis was used to explore the factors related to the deviation of the pogonion point (Pog). Comparison of the two groups showed that the position of the lateral point of the pyriform aperture and the length of the mandibular body exhibited significant asymmetry (P < 0.05). Pog in the UCLP group deviated to the cleft side (1.24 ± 2.28 mm), and was related to B6L(R) to Sagittal plane, CdL(R) to Sagittal plane, and U6L(R) to LS plane. We concluded that significant differences between the cleft and non-cleft sides existed only around the cleft, and not in the deeper regions of the maxillary complex. Functional adaption may be the main reason responsible for chin deviation in UCLP individuals. (J Oral Sci 58, 109-115, 2016).
我们的研究旨在使用锥形束计算机断层扫描（CBCT）检查单侧唇腭裂（UCLP）患者的面部不对称情况，并探究导致这些个体面部下1/3不对称的因素。实验组包括21例非综合征性UCLP青少年患者，而对照组由14例无任何面部裂隙缺陷的患者组成。使用CBCT对两组患者的颌面区域进行扫描，并使用Mimics 10.01软件分析图像。采用多元线性逐步回归分析来探究与颏前点（Pog）偏移相关的因素。两组比较显示，梨状孔外侧点的位置和下颌体长度存在显著不对称（P < 0.05）。UCLP组的Pog向裂隙侧偏移（1.24±2.28 mm），且与B6L（R）至矢状面、CdL（R）至矢状面以及U6L（R）至LS平面有关。我们得出结论，裂隙侧与非裂隙侧之间的显著差异仅存在于裂隙周围，而非上颌复合体的深部区域。功能适应性可能是UCLP个体颏部偏移的主要原因。（《口腔科学杂志》58卷，109 - 115页，2016年）
