Rawandale Nirmalkumar A, Suryawanshi Kishor H
Assistant Professor, Department of Medicine, S.B.H.G.M.C. Dhule, Maharashtra, India .
Associate Professor, Department of Pathology, A.C.P.M. Medical College , Dhule, Maharashtra, India .
J Clin Diagn Res. 2016 Feb;10(2):OD03-4. doi: 10.7860/JCDR/2016/16121.7188. Epub 2016 Feb 1.
Malignant melanoma of esophagus is usually a metastatic tumour rather than a primary tumour. Primary malignant melanoma accounts for less than 0.2% of all esophageal neoplasm. We report a case of primary spindle cell malignant melanoma of esophagus in a 69-year-old male who presented with history of dysphagia since 1 month. Radiological examinations revealed polypoidal growth at lateral aspect of esophagus. Biopsy was reported as grade III squamous cell carcinoma. Video assisted thoracoscopic esophagectomy was performed. Histopathological examination along with immunohistochemistry gave confirmed diagnosis of primary spindle cell malignant melanoma of esophagus. Though a rare entity, due to its aggressive nature and poor prognosis primary malignant melanoma should be one of the differential diagnoses in a patient with polypoidal esophageal mass lesion. Despite radical surgical treatment prognosis is extremely poor.
食管恶性黑色素瘤通常是转移性肿瘤而非原发性肿瘤。原发性恶性黑色素瘤占所有食管肿瘤的比例不到0.2%。我们报告一例69岁男性原发性食管梭形细胞恶性黑色素瘤病例，该患者有1个月的吞咽困难病史。影像学检查显示食管外侧有息肉样肿物。活检报告为III级鳞状细胞癌。遂行电视辅助胸腔镜食管切除术。组织病理学检查及免疫组化确诊为原发性食管梭形细胞恶性黑色素瘤。尽管是罕见病例，但由于其侵袭性和预后不良，原发性恶性黑色素瘤应作为食管息肉样肿物患者的鉴别诊断之一。尽管进行了根治性手术治疗，预后仍然极差。
