Argudín M A, Dodémont M, Vandendriessche S, Rottiers S, Tribes C, Roisin S, de Mendonça R, Nonhoff C, Deplano A, Denis O
National Reference Centre-Staphylococcus aureus, Department of Microbiology, Hôpital Erasme, Université Libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium.
Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.
Eur J Clin Microbiol Infect Dis. 2016 Jun;35(6):1017-22. doi: 10.1007/s10096-016-2632-x. Epub 2016 Apr 4.
Staphylococcus argenteus is a novel Staphylococcus species closely related to Staphylococcus aureus that has been recently described. In this study, we investigated the proportion and the characteristics of S. argenteus recovered from humans in Belgium. S. aureus. human isolates collected in Belgium from 2006 to 2015 (n = 1,903) were retrospectively characterised via the presence of non-pigmented colonies on chocolate agar, spa typing and rpoB sequencing to determine if some of them were in fact S. argenteus. Out of 73 strains non-pigmented on chocolate plates, 3 isolates (0.16 %) showed rpoB sequences, in addition to spa and sequence types (ST2250/t5787, ST2250/t6675, ST3240/t6675), related to S. argenteus. Two of them were methicillin-resistant, harbouring a SCCmec type IV. The three S. argenteus isolates carried genes (sak, scn) of the immune evasion cluster. This first Belgian nationwide analysis showed a low occurrence of S. argenteus. Further studies should be conducted to identify the distribution range and the clinical impact of this new species.
银色葡萄球菌是一种最近被描述的与金黄色葡萄球菌密切相关的新型葡萄球菌。在本研究中，我们调查了在比利时从人类身上分离出的银色葡萄球菌的比例和特征。对2006年至2015年在比利时收集的金黄色葡萄球菌人类分离株（n = 1903）进行回顾性分析，通过巧克力琼脂上无色素菌落的存在、spa分型和rpoB测序来确定其中是否有一些实际上是银色葡萄球菌。在巧克力平板上无色素的73株菌株中，有3株分离株（0.16%）除了spa和序列类型（ST2250/t5787、ST2250/t6675、ST3240/t6675）外，还显示出与银色葡萄球菌相关的rpoB序列。其中两株对甲氧西林耐药，携带IV型葡萄球菌盒式染色体mec（SCCmec）。这三株银色葡萄球菌分离株携带免疫逃避簇的基因（sak、scn）。这项首次在比利时全国范围内进行的分析显示银色葡萄球菌的发生率较低。应开展进一步研究以确定该新物种的分布范围和临床影响。
