Department of Cellular & Molecular Physiology, Yale University, New Haven, Connecticut;
Department of Cellular & Molecular Physiology, Yale University, New Haven, Connecticut; Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University, New Haven, Connecticut; and Department of Neuroscience, Yale University, New Haven, Connecticut
Physiology (Bethesda). 2016 May;31(3):193-200. doi: 10.1152/physiol.00036.2015.
Evolution has endowed vertebrates with the remarkable tactile ability to explore the world through the perception of physical force. Yet the sense of touch remains one of the least well understood senses at the cellular and molecular level. Vertebrates specializing in tactile perception can highlight general principles of mechanotransduction. Here, we review cellular and molecular adaptations that underlie the sense of touch in typical and acutely mechanosensitive vertebrates.
进化赋予了脊椎动物一种非凡的触觉能力,使它们能够通过感知物理力来探索世界。然而,在细胞和分子水平上,触觉仍然是了解最少的感觉之一。专门从事触觉感知的脊椎动物可以突出机械转导的一般原理。在这里,我们回顾了典型和急性机械敏感脊椎动物触觉的细胞和分子适应。