Donnelly J E, Donnelly W J, Thong Y H
Department of Child Health, University of Queensland, Mater Children's Hospital, South Brisbane, Australia.
Ann Allergy. 1989 Apr;62(4):337-41.
The parents of 128 children with asthma were interviewed about their knowledge of asthma medications. Simple understanding of the modes of action of these drugs was present in only 42.2% (for beta 2-agonists), 12.1% (methylxanthines), 11.7% (cromoglycate), 0% (inhaled corticosteroids), and 3.6% (oral corticosteroids) of parents. Simple understanding of when to use these drugs was present in 13.4% (beta 2-agonists), 4% (methylxanthines), 50% (cromoglycate), 47.1% (inhaled corticosteroids), and 0% (oral corticosteroids). Some understanding of the side effects was observed in 51.6% (beta 2-agonists), 40.4% (methylxanthines), 10% (cromoglycate), 5.9% (inhaled corticosteroids), and 25% (oral corticosteroids). Poor parental knowledge about the pharmacology of asthma was underlined by the inclusion of antibiotics, antihistamines, and decongestants as medications used in asthma. This study also uncovered the continuing misuse of compound methylxanthine preparations and non-selective sympathomimetics in a small percentage of patients.
对128名哮喘患儿的家长就其对哮喘药物的了解情况进行了访谈。仅有42.2%的家长(对于β2激动剂)、12.1%的家长(甲基黄嘌呤)、11.7%的家长(色甘酸)、0%的家长(吸入性糖皮质激素)以及3.6%的家长(口服糖皮质激素)对这些药物的作用方式有基本了解。对于何时使用这些药物,有基本了解的家长比例分别为:13.4%(β2激动剂)、4%(甲基黄嘌呤)、50%(色甘酸)、47.1%(吸入性糖皮质激素)以及0%(口服糖皮质激素)。观察到部分家长了解副作用的比例为:51.6%(β2激动剂)、40.4%(甲基黄嘌呤)、10%(色甘酸)、5.9%(吸入性糖皮质激素)以及25%(口服糖皮质激素)。将抗生素、抗组胺药和解充血药列为哮喘治疗用药,凸显出家长对哮喘药理学知识的匮乏。该研究还发现,仍有一小部分患者持续滥用复方甲基黄嘌呤制剂和非选择性拟交感神经药。