Hodges E, Tabbara K F
Department of Ophthalmology, College of Medicine, King Saud University, Saudi Arabia.
Br J Ophthalmol. 1989 Mar;73(3):205-8. doi: 10.1136/bjo.73.3.205.
We studied a total of 23 patients with orbital cellulitis and/or orbital abscess over a period of four years in Saudi Arabia. The study showed a high rate of abscess formation (12/23) and surgical intervention (17/23). Twelve out of 23 patients were 18 or more years of age. Furthermore, 12 of 23 (52%) patients had blind eyes on admission and remained blind after treatment, and one patient died of cavernous sinus thrombosis. Only 7/23 (30%) had a predisposing cause of primary sinus disease. This study of orbital cellulitis in a developing country presents a variation in disease pattern from previous reports and suggests that delay in the initiation of antibiotic therapy may lead to serious complications which may be life threatening. The course and outcome of orbital cellulitis may vary, depending on the predisposing factor, time of onset, associated systemic disease, or delay in initiation of treatment.
在沙特阿拉伯的四年时间里，我们共研究了23例眼眶蜂窝织炎和/或眼眶脓肿患者。研究显示脓肿形成率较高（12/23），手术干预率也较高（17/23）。23例患者中有12例年龄在18岁及以上。此外，23例患者中有12例（52%）入院时患眼已失明，治疗后仍失明，1例患者死于海绵窦血栓形成。只有7/23（30%）有原发性鼻窦疾病这一诱发因素。这项针对发展中国家眼眶蜂窝织炎的研究表明，疾病模式与之前的报告有所不同，提示抗生素治疗开始延迟可能导致严重的、可能危及生命的并发症。眼眶蜂窝织炎的病程和结果可能因诱发因素、发病时间、相关全身性疾病或治疗开始延迟而有所不同。
