Wi Chung-Il, St Sauver Jennifer L, Jacobson Debra J, Pendegraft Richard S, Lahr Brian D, Ryu Euijung, Beebe Timothy J, Sloan Jeff A, Rand-Weaver Jennifer L, Krusemark Elizabeth A, Choi YuBin, Juhn Young J
Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN.
Division of Epidemiology, Mayo Clinic, Rochester, MN.
Mayo Clin Proc. 2016 May;91(5):612-22. doi: 10.1016/j.mayocp.2016.02.011. Epub 2016 Apr 8.
To characterize health disparities in common chronic diseases among adults by socioeconomic status (SES) and ethnicity in a mixed rural-urban community of the United States.
We conducted a cross-sectional study to assess the association of the prevalence of the 5 most burdensome chronic diseases in adults with SES and ethnicity and their interaction. The Rochester Epidemiology Project medical records linkage system was used to identify the prevalence of coronary heart disease, asthma, diabetes, hypertension, and mood disorder using International Classification of Diseases, Ninth Revision codes recorded from January 1, 2005, through December 31, 2009, among all adult residents of Olmsted County, Minnesota, on April 1, 2009. For SES measurements, an individual HOUsing-based index of SocioEconomic Status (HOUSES) derived from real property data was used. Logistic regression models were used to examine the association of the prevalence of chronic diseases with ethnicity and HOUSES score and their interaction.
We identified 88,010 eligible adults with HOUSES scores available, of whom 48,086 (54.6%) were female and 80,699 (91.7%) were non-Hispanic white; the median (interquartile range) age was 45 years (30-58 years). Overall and in the subgroup of non-Hispanic whites, SES measured by HOUSES was inversely associated with the prevalence of all 5 chronic diseases independent of age, sex, and ethnicity (P<.001). While an association of ethnicity with disease prevalence was observed for all the chronic diseases, SES modified the effect of ethnicity for clinically less overt conditions (interaction P<.05 for each condition [diabetes, hypertension, and mood disorder]) but not for coronary heart disease, a clinically more overt condition.
In a mixed rural-urban setting with a predominantly non-Hispanic white population, health disparities in chronic diseases still exist across SES. The extent to which SES modifies the effect of ethnicity on the risk of chronic diseases may depend on the nature of the disease.
在美国城乡混合社区中,按社会经济地位(SES)和种族特征描述成年人常见慢性病的健康差异。
我们开展了一项横断面研究,以评估成年人中5种最具负担的慢性病患病率与SES和种族之间的关联及其相互作用。利用罗切斯特流行病学项目医疗记录链接系统,通过2005年1月1日至2009年12月31日期间记录的国际疾病分类第九版编码,确定明尼苏达州奥尔姆斯特德县所有成年居民在2009年4月1日时冠心病、哮喘、糖尿病、高血压和情绪障碍的患病率。对于SES测量,使用了基于房地产数据得出的个人住房社会经济地位指数(HOUSES)。采用逻辑回归模型检验慢性病患病率与种族和HOUSES得分之间的关联及其相互作用。
我们确定了88010名有HOUSES得分的合格成年人,其中48086名(54.6%)为女性,80699名(91.7%)为非西班牙裔白人;年龄中位数(四分位间距)为45岁(30 - 58岁)。总体而言,在非西班牙裔白人亚组中,由HOUSES衡量的SES与所有5种慢性病的患病率呈负相关,且独立于年龄、性别和种族(P <.001)。虽然观察到所有慢性病的患病率都与种族有关,但SES改变了种族对临床症状较轻疾病的影响(每种疾病[糖尿病、高血压和情绪障碍]的相互作用P <.05),但对冠心病这种临床症状较明显的疾病没有影响。
在以非西班牙裔白人为主的城乡混合环境中,SES不同,慢性病的健康差异仍然存在。SES改变种族对慢性病风险影响的程度可能取决于疾病的性质。