Al-Kuraishy Hayder M
Department of Pharmacology, Toxicology and Medicine College of Medicine Al-Mustansiriya University, P.O. Box 14132, Iraq, Baghdad.
J Intercult Ethnopharmacol. 2015 Dec 22;5(1):7-13. doi: 10.5455/jice.20151123043202. eCollection 2016 Jan-Feb.
The present study investigates the effect of combined treatment with Ginkgo biloba and/or Rhodiola rosea on psychomotor vigilance task (PVT) and short-term working memory accuracy.
A total number of 112 volunteers were enrolled to study the effect of G. biloba and R. rosea on PVT and short-term working memory accuracy as compared to placebo effects, the central cognitive effect was assessed by critical flicker-fusion frequency, PVT, and computerized N-back test.
Placebo produced no significant effects on all neurocognitive tests measure P > 0.05 in normal healthy volunteers, G. biloba or R. rosea improve PVT and low to moderate working memory accuracy, The combined effect of R. rosea and G. biloba leading to more significant effect on PVT, all levels of short-term working memory accuracy and critical fusion versus flicker P < 0.01, more than of G. biloba or R. rosea when they used alone.
The combined effect of R. rosea and G. biloba leading to a more significant effect on cognitive function than either G. biloba or R. rosea when they used alone.
本研究调查银杏叶和/或红景天联合治疗对精神运动警觉任务（PVT）和短期工作记忆准确性的影响。
共招募了112名志愿者，以研究银杏叶和红景天与安慰剂效应相比对PVT和短期工作记忆准确性的影响，通过临界闪烁融合频率、PVT和计算机化N-back测试评估中枢认知效应。
在正常健康志愿者中，安慰剂对所有神经认知测试均无显著影响（P>0.05），银杏叶或红景天可改善PVT和中低水平的工作记忆准确性，红景天和银杏叶的联合作用对PVT、各级短期工作记忆准确性和临界融合与闪烁的影响更为显著（P<0.01），比单独使用银杏叶或红景天的效果更佳。
红景天和银杏叶的联合作用对认知功能的影响比单独使用银杏叶或红景天更为显著。
