Ramesh Asha, Varghese Sheeja Saji, Doraiswamy Jayakumar Nadathur, Malaiappan Sankari
Department of Periodontics, Saveetha Dental College and Hospital, Chennai, India.
J Intercult Ethnopharmacol. 2016 Jan 27;5(1):92-6. doi: 10.5455/jice.20160122065556. eCollection 2016 Jan-Feb.
Herbal medicines have long been used as a traditional mode of therapy for various ailments in India. They are being used increasingly as dietary supplements to ward off common diseases. Periodontal diseases are highly prevalent and can affect up to 90% of the world population. Gingivitis is the mild form whereas periodontitis results in an irreversible loss of supporting structures of the teeth. Even though periodontal pathogens form a crucial component in the etiopathogenesis of periodontitis, there is a growing body of evidence suggesting oxidative stress playing a pivotal role in the disease initiation and progression. Studies have shown a direct correlation between increased levels of biomarkers for tissue damage induced by reactive oxygen species (ROS) to the severity of periodontal disease. Thus, the focus of attention has revolved back to herbal medicines due to their wide spectrum of biological and medicinal activities, lower costs, and higher safety margin. Internet databases Pubmed and Google Scholar were searched, and the most relevant articles were considered for review. This review briefly describes the various herbs with antioxidant capacity and their potency in the treating periodontal disease.
在印度，草药长期以来一直被用作治疗各种疾病的传统疗法。它们越来越多地被用作膳食补充剂以预防常见疾病。牙周疾病非常普遍，可影响多达90%的世界人口。牙龈炎是较轻的形式，而牙周炎则会导致牙齿支持结构不可逆转的丧失。尽管牙周病原体在牙周炎的病因发病机制中是一个关键组成部分，但越来越多的证据表明氧化应激在该疾病的发生和发展中起关键作用。研究表明，活性氧（ROS）诱导的组织损伤生物标志物水平升高与牙周疾病的严重程度直接相关。因此，由于草药具有广泛的生物和药用活性、较低的成本以及更高的安全边际，人们的注意力又回到了草药上。检索了互联网数据库PubMed和谷歌学术，并考虑了最相关的文章进行综述。本综述简要描述了具有抗氧化能力的各种草药及其治疗牙周疾病的效力。
