Institute of Analytical and Bioanalytical Chemistry, Ulm University, 89069 Ulm, Germany; email:
Annu Rev Anal Chem (Palo Alto Calif). 2016 Jun 12;9(1):45-68. doi: 10.1146/annurev-anchem-071015-041507. Epub 2016 Apr 6.
Infrared spectroscopy in the 3-20 μm spectral window has evolved from a routine laboratory technique into a state-of-the-art spectroscopy and sensing tool by benefitting from recent progress in increasingly sophisticated spectra acquisition techniques and advanced materials for generating, guiding, and detecting mid-infrared (MIR) radiation. Today, MIR spectroscopy provides molecular information with trace to ultratrace sensitivity, fast data acquisition rates, and high spectral resolution catering to demanding applications in bioanalytics, for example, and to improved routine analysis. In addition to advances in miniaturized device technology without sacrificing analytical performance, selected innovative applications for MIR spectroscopy ranging from process analysis to biotechnology and medical diagnostics are highlighted in this review.
红外光谱在 3-20μm 的光谱窗口中，受益于日益复杂的光谱采集技术和用于产生、引导和探测中红外（MIR）辐射的先进材料的进步，已经从常规实验室技术发展成为一种最先进的光谱和传感工具。如今，MIR 光谱提供了具有痕量至超痕量灵敏度、快速数据采集速度和高光谱分辨率的分子信息，满足了生物分析等苛刻应用以及改进常规分析的需求。除了在不牺牲分析性能的情况下实现小型化设备技术的进步外，本文还重点介绍了 MIR 光谱在从过程分析到生物技术和医学诊断等各个领域的一些创新应用。
