HIV 感染老年患者抗逆转录病毒治疗依从性的相关因素
Correlates of Antiretroviral Therapy Adherence among HIV-Infected Older Adults.
作者信息
McCoy Katryna, Waldrop-Valverde Drenna, Balderson Benjamin H, Mahoney Christine, Catz Sheryl
机构信息
University of Washington Bothell, School of Nursing & Health Studies, Bothell, WA, USA
Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
出版信息
J Int Assoc Provid AIDS Care. 2016 May;15(3):248-55. doi: 10.1177/2325957416642019. Epub 2016 Apr 12.
BACKGROUND
Despite the success of antiretroviral therapy (ART), HIV-infected older African Americans experience higher mortality rates compared to their white counterparts. This disparity may be partly attributable to the differences in ART adherence by different racial and gender groups. The purpose of this study was to describe demographic, psychosocial, and HIV disease-related factors that influence ART adherence and to determine whether race and gender impact ART adherence among HIV-infected adults aged 50 years and older.
METHODS
This descriptive study involved a secondary analysis of baseline data from 426 participants in "PRIME," a telephone-based ART adherence and quality-of-life intervention trial. Logistic regression was used to examine the association between independent variables and ART adherence.
RESULTS
Higher annual income and increased self-efficacy were associated with being ≥95% ART adherent. Race and gender were not associated with ART adherence.
CONCLUSION
These findings indicated that improvements in self-efficacy for taking ART may be an effective strategy to improve adherence regardless of race or gender.
背景
尽管抗逆转录病毒疗法（ART）取得了成功，但与白人相比，感染艾滋病毒的老年非裔美国人死亡率更高。这种差异可能部分归因于不同种族和性别群体在ART依从性上的差异。本研究的目的是描述影响ART依从性的人口统计学、心理社会和艾滋病毒疾病相关因素，并确定种族和性别是否会影响50岁及以上感染艾滋病毒成年人的ART依从性。
方法
这项描述性研究涉及对“PRIME”（一项基于电话的ART依从性和生活质量干预试验）中426名参与者的基线数据进行二次分析。采用逻辑回归分析来检验自变量与ART依从性之间的关联。
结果
较高的年收入和增强的自我效能感与ART依从率≥95%相关。种族和性别与ART依从性无关。
结论
这些发现表明，提高服用ART的自我效能感可能是提高依从性的有效策略，无论种族或性别如何。
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