Nassar Amani, Ghomey Soheir, El Gohary Yosria, El-Desoky Fatma
a Departments of Dermatology , Venereology and Andrology, Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.
b Department of Pathology , Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.
J Cosmet Laser Ther. 2016 Oct;18(6):330-4. doi: 10.1080/14764172.2016.1175633. Epub 2016 Jun 2.
Striae distensae (SD) is a challenging cosmetic problem for which various treatment modalities have been applied. Our aim was to evaluate the efficacy and tolerability of needling therapy versus microdermabrasion with sonophoresis in the treatment of SD.
Forty female patients with SD (mean duration 2.98 ± 2.66) were enrolled in this study. Patients were assigned to two groups, Group 1 treated with needling therapy and Group 2 treated by microdermabrasion with sonophoresis. In Group 1, three sessions of needling therapy were performed for each patient with 4-week interval between the sessions, while in Group 2, ten sessions of combined microdermabrasion and sonophoresis were performed for each patient. Skin biopsies were taken from the most atrophic site stained with hematoxylin and eosin stain and Masson trichrome stains to study the histopathological changes and efficacy of treatment, respectively.
There was a significant clinical improvement in SD in Group 1 compared with Group 2. Amount of collagen, number of fibroblasts, and epidermal thickness increased in the dermis at the end of treatment sessions (90% in Group 1 compared to 50% in Group 2).
Needling therapy is an easy, safe, and economic method and considered as a suitable modality in management of striae.
膨胀纹（SD）是一个具有挑战性的美容问题，针对此问题已应用了多种治疗方式。我们的目的是评估针刺疗法与超声导入微针磨皮术治疗膨胀纹的疗效和耐受性。
40名患有膨胀纹的女性患者（平均病程2.98±2.66）纳入本研究。患者被分为两组，第1组采用针刺疗法治疗，第2组采用超声导入微针磨皮术治疗。第1组中，每位患者进行3次针刺治疗，每次治疗间隔4周；而在第2组中，每位患者进行10次微针磨皮术与超声导入联合治疗。分别从最萎缩部位取皮肤活检组织，进行苏木精-伊红染色和马松三色染色，以研究组织病理学变化和治疗效果。
与第2组相比，第1组膨胀纹有显著的临床改善。治疗结束时，第1组真皮中的胶原蛋白含量、成纤维细胞数量和表皮厚度增加（第1组为90%，第2组为50%）。
针刺疗法是一种简便、安全且经济的方法，被认为是治疗膨胀纹的合适方式。
