Nic Lochlainn Laura, Mandal Sema, de Sousa Rita, Paranthaman Karthik, van Binnendijk Rob, Ramsay Mary, Hahné Susan, Brown Kevin E
National Institute for Public Health and the Environment, Centre for Infectious Disease Control, Bilthoven, the Netherlands.
Euro Surveill. 2016;21(13). doi: 10.2807/1560-7917.ES.2016.21.13.30177.
This report describes a joint measles outbreak investigation between public health officials in the United Kingdom (UK) and the Netherlands following detection of a measles cluster with a unique measles virus strain. From 1 February to 30 April 2014, 33 measles cases with a unique measles virus strain of genotype B3 were detected in the UK and the Netherlands, of which nine secondary cases were epidemiologically linked to an infectious measles case travelling from the Philippines. Through a combination of epidemiological investigation and sequence analysis, we found that measles transmission occurred in flight, airport and household settings. The secondary measles cases included airport workers, passengers in transit at the same airport or travelling on the same flight as the infectious case and also household contacts. This investigation highlighted the particular importance of measles genotyping in identifying transmission networks and the need to improve vaccination, public health follow-up and management of travellers and airport staff exposed to measles.
本报告描述了在检测到具有独特麻疹病毒株的麻疹聚集性病例后，英国和荷兰的公共卫生官员联合开展的麻疹疫情调查。2014年2月1日至4月30日，在英国和荷兰检测到33例具有基因型B3独特麻疹病毒株的麻疹病例，其中9例二代病例在流行病学上与一名来自菲律宾的麻疹感染病例有关。通过流行病学调查和序列分析相结合，我们发现麻疹传播发生在航班上、机场和家庭环境中。二代麻疹病例包括机场工作人员、在同一机场转机或与感染病例乘坐同一航班的乘客以及家庭接触者。这项调查突出了麻疹基因分型在识别传播网络方面的特殊重要性，以及改进疫苗接种、公共卫生随访以及对接触麻疹的旅行者和机场工作人员进行管理的必要性。
