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1
Safety and Upper Respiratory Pharmacokinetics of the Hemagglutinin Stalk-Binding Antibody VIS410 Support Treatment and Prophylaxis Based on Population Modeling of Seasonal Influenza A Outbreaks.基于季节性流感 A 暴发的群体药代动力学模型，血凝素茎结合抗体 VIS410 的安全性和上呼吸道药代动力学支持治疗和预防。
EBioMedicine. 2016 Feb 26;5:147-55. doi: 10.1016/j.ebiom.2016.02.021. eCollection 2016 Mar.
2
Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans.人类流感病毒血凝素茎部反应性抗体的年龄依赖性和亚型特异性
mBio. 2016 Jan 19;7(1):e01996-15. doi: 10.1128/mBio.01996-15.
3
The Hemagglutinin Stem-Binding Monoclonal Antibody VIS410 Controls Influenza Virus-Induced Acute Respiratory Distress Syndrome.血凝素茎结合单克隆抗体 VIS410 可控制流感病毒诱发的急性呼吸窘迫综合征。
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2118-31. doi: 10.1128/AAC.02457-15. Print 2016 Apr.
4
A broadly neutralizing human monoclonal antibody is effective against H7N9.一种广泛中和的人源单克隆抗体对H7N9有效。
Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10890-5. doi: 10.1073/pnas.1502374112. Epub 2015 Aug 17.
5
Global circulation patterns of seasonal influenza viruses vary with antigenic drift.季节性流感病毒的全球传播模式会随抗原漂移而变化。
Nature. 2015 Jul 9;523(7559):217-20. doi: 10.1038/nature14460. Epub 2015 Jun 8.
6
Zanamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments.扎那米韦治疗成人和儿童流感：临床研究报告的系统评价和监管意见摘要。
BMJ. 2014 Apr 9;348:g2547. doi: 10.1136/bmj.g2547.
7
Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo.广泛中和血凝素茎特异性抗体需要 FcγR 相互作用才能在体内预防流感病毒。
Nat Med. 2014 Feb;20(2):143-51. doi: 10.1038/nm.3443. Epub 2014 Jan 12.
8
Cochrane re-arranged: support for policies to vaccinate elderly people against influenza.科克伦调整：支持为老年人接种流感疫苗的政策。
Vaccine. 2013 Dec 5;31(50):6030-3. doi: 10.1016/j.vaccine.2013.09.063. Epub 2013 Oct 3.
9
Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies.自组装流感纳米颗粒疫苗诱导产生广泛中和 H1N1 的抗体。
Nature. 2013 Jul 4;499(7456):102-6. doi: 10.1038/nature12202. Epub 2013 May 22.
10
Influenza-associated hospitalizations in the United States.美国与流感相关的住院情况。
JAMA. 2004 Sep 15;292(11):1333-40. doi: 10.1001/jama.292.11.1333.

One Against All: A Broadly Influenza Neutralizing Man-made Monoclonal Antibody Passes Phase I.

作者信息

Saelens Xavier

机构信息

Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.

出版信息

EBioMedicine. 2016 Feb 26;5:16-7. doi: 10.1016/j.ebiom.2016.02.036. eCollection 2016 Mar.

DOI:10.1016/j.ebiom.2016.02.036
PMID:27077102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4816848/
Abstract
摘要