Verhoef Talitha I, Doshi Parita, Lehner Dan, Morris Stephen
Department of Applied Health Research, University College London, Gower Street, London, WC1E 6BT, UK.
Oomph! Wellness Ltd, London, UK.
BMC Geriatr. 2016 Apr 18;16:83. doi: 10.1186/s12877-016-0261-y.
Oomph! Wellness organises interactive exercise and activity classes (Oomph! classes) for older people in care homes. We investigated the cost-effectiveness of Oomph! classes.
Health-related quality of life was measured using the EQ-5D-5 L questionnaire at three time points; 3 months and 1 week prior to the start of the classes and after 3 months of Oomph! classes. Costs included the costs of organising the classes, training instructors and health service use (General Practitioner (GP) and hospital outpatient visits). To determine the cost-effectiveness of Oomph! classes, total costs and quality-adjusted life-years (QALYs) during the 3 months after initiation of the classes were compared to the total costs and QALYs of the 3 months prior to the classes and extrapolated to a 1-year time horizon. Uncertainty was taken into account using one-way and probabilistic sensitivity analysis.
Sixteen residents completed all three EQ-5D-5 L questionnaires. There was a decrease in mean health related quality of life per participant in the 3 months before Oomph! classes (0.56 to 0.52, p = 0.26) and an increase in the 3 months after the start of Oomph! classes (0.52 to 0.60, p = 0.06), but the changes were not statistically significant. There were more GP visits after the start of Oomph! classes and fewer hospital outpatient visits, leading to a slight decrease in NHS costs (mean £132 vs £141 per participant), but the differences were not statistically significant (p = 0.79). In the base case scenario, total costs for Oomph! classes were £113 higher per participant than without Oomph! classes (£677 vs £564) and total QALYs were 0.074 higher (0.594 vs 0.520). The incremental costs per QALY gained were therefore £1531. The 95 % confidence intervals around the cost/QALY gained varied from dominant to dominated, meaning there was large uncertainty around the cost-effectiveness results. Given a willingness to pay threshold of £20,000 per QALY gained, Oomph! classes had a 62 %-86 % probability of being cost-effective depending on the scenario used.
Preliminary evidence suggests that Oomph! classes may be cost-effective, but further evidence is needed about its impact on health-related quality of life and health service use.
“活力!健康”组织为养老院中的老年人开展互动式锻炼和活动课程(“活力!课程”)。我们对“活力!课程”的成本效益进行了调查。
使用EQ-5D-5L问卷在三个时间点测量与健康相关的生活质量;课程开始前3个月和1周,以及“活力!课程”进行3个月后。成本包括组织课程、培训指导员和医疗服务使用(全科医生(GP)和医院门诊就诊)的费用。为了确定“活力!课程”的成本效益,将课程开始后3个月的总成本和质量调整生命年(QALYs)与课程开始前3个月的总成本和QALYs进行比较,并推算至1年的时间范围。使用单向和概率敏感性分析考虑不确定性。
16名居民完成了所有三份EQ-5D-5L问卷。在“活力!课程”开始前的3个月里,每位参与者的平均健康相关生活质量有所下降(从0.56降至0.52,p = 0.26),而在“活力!课程”开始后的3个月里有所上升(从0.52升至0.60,p = 0.06),但这些变化没有统计学意义。“活力!课程”开始后,全科医生就诊次数增多,医院门诊就诊次数减少,导致国民保健服务成本略有下降(每位参与者平均132英镑对141英镑),但差异无统计学意义(p = 0.79)。在基础案例中,“活力!课程”每位参与者的总成本比没有“活力!课程”时高113英镑(677英镑对564英镑),总QALYs高0.074(0.594对0.520)。因此,每获得一个QALY的增量成本为1531英镑。获得的成本/QALY的95%置信区间从占优到被占优不等,这意味着成本效益结果存在很大的不确定性。假设每获得一个QALY的支付意愿阈值为20000英镑,根据所使用的情景,“活力!课程”具有成本效益的概率为62%-86%。
初步证据表明,“活力!课程”可能具有成本效益,但需要更多关于其对健康相关生活质量和医疗服务使用影响的证据。